目的：研究股骨近端防旋髓内钉（PFNA）内固定与鲑鱼降钙素（SCT）联合治疗老年股骨粗隆间骨折的效果及其对骨密度（BMD）的影响。方法将老年股骨粗隆间骨折患者82例随机分成SCT组与对照组，各41例。两组均行PFNA内固定术，对照组术后应用钙尔奇D600，SCT组在对照组的基础上加用SCT，比较两组的手术时间、术中出血量、术后住院时间及骨折愈合时间等手术指标，随访比较两组手术前后Harris评分、视觉模拟评分（VAS）、BMD以及髋关节功能。结果 SCT组的住院时间与骨折愈合时间明显短于对照组，VAS降低较对照组明显（P<0.05或P<0.01）；术后6个月，SCT组BMD值和Harris评分显著高于对照组（P<0.05或P<0.01），髋关节优良率为82.93%，显著高于对照组的65.85%（P<0.05）；两组手术并发症与不良反应比较差异无统计学意义（P>0.05）。结论 PFNA内固定治疗老年股骨粗隆间骨折具有显著效果，配合SCT治疗可提高BMD，促进骨折愈合，改善患者的生活质量。%Objective To investigate the efficacy of PFNA fixation combined with salmon calcitonin (SCT) in the treat-ment of senile femoral intertrochanteric fracture and the effects on bone mineral density (BMD). Methods 82 cases of senile femoral intertrochanteric fracture patients were randomly divided into SCT group and control group, with 41 cas-es in each group. Both groups underwent PFNA fixation, the control group received caltrate D600 treatment, SCT group received SCT on the basis of the control group, the surgical indexes such as operative time, blood loss, hospitai stay time and bone healing time of the two groups were compared, the Harris score, VAS score, BMD and hip function be-fore and after surgery of the two groups were followed and compared. Results The hospital stay time and bone healing time in SCT group was significantly shorter than the control group, and the VAS reduction was significantly better than the control group (P<0.05 or P<0.01);postoperative 6 months, the BMD and Harris score in SCT group was significant-ly higher than control group (P<0.05 or P< 0.01), the excellent rate was 82.93%, significantly higher than 65.85% in control group (P<0.05);the surgical complications and adverse reactions in the two groups were not statistically signifi-cant different (P>0.05). Conclusion PFNA fixation in the treatment of senile femoral intertrochanteric fracture has a signif-icant effect, combined with salmon calcitonin can improve BMD, promote healing and improve the quality of life of patients.
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