目的：监测重症监护病房(ICU)多重耐药菌的临床分布情况，对相关因素进行干预，降低感染率。方法以2013年和2014年综合ICU住院患者为监测对象。调查分析2013、2014年ICU的多重耐药菌感染患者的临床资料。对病房周围环境、物品表面、工作人员手等进行监测。观察工作人员操作与患者感染之间的关系。对感染因素进行干预。结果2013年住院患者301例，耐药菌感染患者93例，其中院内感染32例，占感染人数的34.41%；2014年住院患者369例，耐药菌感染患者118例，其中院内感染25例，占感染人数的21.19%；两年比较差异有统计学意义(P<0.05)。两年中均以多重耐药的鲍曼不动杆菌感染为最多，分别占79.57%和81.36%；第2位是多重耐药的铜绿假单胞菌感染，分别占11.83%和8.48%。结论对综合ICU多重耐药菌定植和感染患者进行监测，加强薄弱环节的管理，能够降低院内感染的发生。%Objective To monitor the clinical distribution of multiple drug-resistant bacteria in ICU, intervene the rele-vant factors, in order to reduce the infection rate. Methods The patient in ICU from the begin of 2013 to the end of 2014 were monitored. The clinical data of all patients infected by multiple drug-resistant bacteria were investigated and analyzed. All about the ward environment, object surface, hands of staffs and so on were monitored. The relation-ship between the operation of staffs and the infection of the patients was observed, and the infection factors were inter-vened. Results In 2013, 93 patients were infected by multiple drug-resistant bacteria among all 301 patients in ICU, in which 32 patients belong to nosocomial infection, accounting for 34.41% of the infections; in 2014, 118 patients were infected by multiple drug-resistant bacteria among all 369 patients in ICU, among which, 25 patients belong to nosoco-mial infection, accounting for 21.19% of the infections; in 2014 the nosocomial infection cases decline compared with those in 2013, the difference was statistically significant (P < 0.05). In these two years, the most common multiple drug-resistance bacteria was the acinetobacter baumannii and the second was the pseudomonas aeruginosa. Multiple drug resistance of acinetobacter baumannii accounted for 79.57% and 81.36% respectively. Multiple drug resistance of pseudomonas aeruginosa accounted for 11.83% and 8.48% respectively. Conclusion Monitoring the multiple drug-re-sistant bacteria planting in ICU and the infected patients, intensify administration in some weaknesses can reduce the occurrence of nosocomial infection.
展开▼
