Objective To investigate the distribution and resistance of pathogenic bacteria isolated from the blood culture specimens collected form Jan 2009 to Dec 2010. Methods A total of 3,731 blood samples were culture by BacT/ Alert 3D240, using Vitek 2 Compact for identification and drug sensitivity analysis. Results 276 stains were isolated from 275 patients, the isolates included Gram-negative baceria(62.9%), Gram-positive baceria (32.4), and fungi (5.09%). Escherichia coli is the main pathogen (88,32.0%). Most of the pathogens were isolated in the ICU (55,20.0%), followed by tumors in hematology department (42, 15.3%); surgical infections was most happen in the urology department 14, 5.09%); Gram-negative bacilli to imipenem and amikacin, laxilin/tazobactam is more sensitive. Staphylococcus to vancomycin, rifampicin, moxifloxacin and 1-ofloxacin is more sensitive. Conclusion The results of blood cultures can provide a basis for clinical antimicrobial treatment, and it is significant for hospital infection and to improve cure rates.%目的 了解医院2009年1月至2010年12月血培养病原菌菌群分布及常见致病菌的耐药情况.方法 血液标本在BacT/Alert 3D240全自动培养仪中培养,采用Vitek 2 Compact全自动鉴定药敏分析系统作鉴定及药敏分析.结果 275例血培养阳性患者共分离出细菌276株,其中革兰阴性菌173株,占62.9％,革兰阳性菌89株,占32.4％,真菌14株,占5.09％,感染率最高的细菌是大肠埃希菌88株,占32.0％.血液感染中ICU最高,55株,占20.0％,其次为肿瘤血液科,42株,15.3％;外科感染中最高的为泌尿外科,14株,5.09％;阴性杆菌对亚胺培南、阿米卡星、派拉西林/三唑巴坦较为敏感.葡萄球菌对万古霉素、利福平、莫西沙星和左旋氧氟沙星较敏感.结论 及时了解血培养结果可以对临床抗菌治疗提供依据,提高治愈率,对控制医院感染具有重要意义.
展开▼
