The pathogenesis of hepatocellular carcinoma ( HCC) is a cancer with high morbidity and mortali-ty, its early diagnosis and treatment is still very difficult .Emerging evidences indicate that MicroRNAs ( miRNAs) can play roles of oncogenes or tumor suppressor genes in the pathogenesis of HCC ,by regulating all aspects of basic cellular processes , including the regulation of cell cycle and apoptosis .This paper reviews the role of miRNAs in reg-ulation of cell cycle and apoptosis of HCC .%肝细胞癌（ HCC）是一种发病率及病死率较高的恶性肿瘤，临床上早期诊断及治疗HCC仍然相当困难。最近研究表明，MicroRNAs（miRNAs）能调控细胞基本过程的各个环节，包括对细胞周期及细胞凋亡的调节，从而在HCC发病机制中发挥促癌或抑癌基因的作用。该文对miRNAs在肝细胞癌细胞周期及凋亡中调节作用的研究进展作一综述。
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