Objective To analyze the neonatal congenital malformation and characterize the dynamic characteristics of birth defects in Xianyang City so as to provide some basis for early intervention and reducing the incidence of congenital malformation. Methods The data of newborns with congenital malformation detected by naked eye delivered in our hospital in 2010 were retrospectively studied. Results Among 5 670 newborns delivered in our hospital, 49 were found with congenital malformation, with an incidence rate of 86. 42/10 000, and the incidence rate in countryside was significantly higher than that in towns and cities. The major congenital malformations were polysyndactyly and syndactyly, cleft palate and cleft lip, spina bifida, meningocele, talipes equinovarus, and ambiguous genitalia. The cesarean section rate of defect infants was 47％. Conclusion We should strengthen the defect infants monitoring, decrease the cesarean section rate of defect infants, and do well in third-level prevention.%目的 通过对新生儿先天畸形分析,掌握本地区出生缺陷的发生动态和规律,为早期干预、减少先天畸形的发生提供依据.方法 对全年住院分娩的新生儿出生后肉眼可见先天畸形资料进行分析.结果 全年共分娩新生儿5 670人,先天畸形儿49例,发生率为86.42/万,农村明显高于城镇.其中多指(趾)、并指(趾);唇裂;腭裂、脊柱裂、脊膜膨出;马蹄内翻足;外生殖器畸形占前5位.缺陷儿剖宫产率47%.结论 加强出生缺陷监测工作,降低缺陷儿的剖宫产率,做好出生缺陷三级预防工作.
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