Objective To examine the therapeutic efficacy of intralesional injection of compound betamethasone combined with low concentration 5-fluorouracil.Methods 87 patients were divided into group A,B and C.30 patients in group A were treated with intralesional injection of 5-fluorouracil.29 patients in group B received treatment of compound betamethasone.28 patients in group C were treated with a mixture of compound betamethasone and low concentration 5-fluorouracil.Three groups of patients were injected once every three week,with a total of four times.All the patients were observed respectively on month 1,3 and 12 after the start of treatment.Results A total of 81 patients completed treatment according to the requirement.In the 12-month follow-up,the efficiency of group A,B and C were 32.0％,58.6％ and 70.4％,respectively.The efficiency of group C was obviously higher than that of group A and B.Conclusion The combination therapy for keloid is safe and effective by using compound betamethasone and low concentration 5-fluorouracil.%目的 探讨低浓度5-氟尿嘧啶(5-FU)与复方倍他米松混合注射治疗瘢痕疙瘩的疗效.方法 将该院87例患者分成A、B、C3组.对A组(n=30)患者行单纯低浓度5-FU注射,对B组(n=29)患者行单纯复方倍他米松注射,对C组(n=28)患者行低浓度5-FU与复方倍他米松的混合液注射,3组患者均每隔3周注射1次,共4次.分别于治疗后第1、3、12个月进行随访.结果 共有81例患者按要求完成疗程,在第12个月随访时,A、B、C组的有效率分别为32.0％、58.6％、70.4％,C组患者有效率明显高于A、B组.结论 低浓度5-FU与复方倍他米松联合治疗瘢痕疙瘩,安全有效.
展开▼
