目的：探讨药师参与肝脓肿抗感染治疗方案优化的药学实践。方法：针对1例肝脓肿患者，药师参与临床查房，在分析患者病情之后，根据抗菌药物的药效学特点，建议用美洛西林舒巴坦取代头孢吡肟、左氧氟沙星与甲硝唑的联合用药，临床医师采纳了建议。结果：更改抗感染治疗方案后，疗效得到了保证，且药品不良反应减少，抗菌药物使用强度降低。结论：临床药师参与临床药物治疗，发挥自身药学专长，提供药学服务，可促进医疗质量的提高。%OBJECTIVE:To probe into the pharmaceutical practice for anti-infection treatment optimization in treatment of liver abscess by pharmacists .METHODS:Pharmacists participated in clinical ward rounds .After examining the ill condition of the patient with liver abscess , according to the pharmacodynamic characteristics of antimicrobial agents, the pharmacists suggested that the drug combination of cefepime , levofloxacin and metronidazole should be replaced by mezlocillin and sulbactam .The clinicians adopt the proposal .RESULTS:After the change of anti-infection treatment , the quality of medical care was assured , the adverse drug reactions were reduced , and the intensity of the antibacterial medicine also decreased .CONCLUSIONS:The clinical pharmacists participate into the clinical treatment , play their pharmaceutical specialty and provide pharmaceutical care can promote the improvement of medical quality . KEYWORDS Clinical pharmacists;Drug-induced liver injury;Liver abscess;Metronidazole;Cefepime;antibiotics use density.
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