研究生长时间为55 d~75 d苦荞全叶及其醇提物对高脂血症仓鼠血脂调节作用。雄性仓鼠适应环境1周后，随机分为5组（n=8），分别为空白组、模型组、苦荞全叶组和苦荞叶醇提物低、高剂量组。饲喂6周后眼底静脉丛取血，断颈处死，测定血清与肝脏中总胆固醇（TC）、甘油三酯（TG）、高密度脂蛋白胆固醇（HDL-C）和丙二醛（MDA）等各项指标。与模型对照组相比，苦荞全叶及其醇提物各剂量组血清、肝脏和粪便中TC、TG含量均极显著降低（P<0.01），血清中HDL-C极显著增高，动脉粥样硬化指数（AI）极显著降低（P<0.01），血清和肝脏中的MDA含量均极显著降低（P<0.01）。苦荞全叶及其醇提物对高脂血症仓鼠具有降血脂的作用。%This study was conducted to investigate the effects of tartay buckwheat leaves and its alcohol extracts on hypolipidemic hamsters. Male hamsters were randomly divided into six groups (n=8):normal group, model group, low-dose and high-dose groups of tartay buckwheat leaves alcohol extracts and tartay buckwheat leaves group. After feeding 6 weeks, hyperlipidemia indicators were tested. Compared with the model group, the total cholesterol (TC) and triglyceride concentrations (TG) , atherogenic index of serum and liver were significantly decreased by feeding the tartay buckwheat leaves and alcohol extracts; the concentration of high density lipoprotein cholesterol in serum exhibited a significantly increase. Meanwhile , the content of MDA was decreased in serum and liver. The results suggested that the tartay buckwheat leaves and alcohol extracts had hypolipidemic activity.
展开▼
