• 主题
高级搜索  >
历史搜索 清空历史
首页> 中文期刊> 《现代肿瘤医学》 >18F-FDG PET/CT联合血清肿瘤标志物对肺部病变的诊断价值

18F-FDG PET/CT联合血清肿瘤标志物对肺部病变的诊断价值

         
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

目的:评估 18F-FDG PET/CT联合血清肿瘤标志物对肺部病变的诊断价值.方法:回顾性分析2013年9月至2016年1月因肺部病变在本院行 18F-FDG PET/CT显像, 并在显像2周内行血清肿瘤标志物细胞角蛋白19片段 (CYFRA21-1) 、神经元特异性烯醇化酶 (NSE) 、癌胚抗原 (CEA) 检测的135例患者的临床资料, 比较PET/CT和血清肿瘤标志物对肺部病变的诊断价值.结果:在灵敏性、准确性和阴性预测值方面, PET/CT的诊断价值明显高于单项血清肿瘤标志物及其联合组 (P=0. 000) .在特异性方面, PET/CT的诊断价值低于CEA (P <0. 05) , 与其他各组比较无明显统计学差异 (P> 0. 05) .在阳性预测值方面, PET/CT与各血清肿瘤标志物之间无明显统计学差异 (P> 0. 05) .结论: 18F-FDG PET/CT具有很高的灵敏度, 而血清肿瘤标志物特异度较高, 因此, 将二者结合进行综合分析有助于提高 18F-FDG PET/CT的诊断信心和准确率.%Objective: To compare the diagnostic value of 18F-FDG PET/CT and lung cancer tumor markers in the diagnosis of lung lesions. Methods: A retrospective analysis was performed on the patients with lung lesions in our hospital from September 2013 to January 2016, who underwent 18F-FDG PET/CT imaging and took a serum tumor markers (CYFRA21-1, NSE, CEA) test in two weeks, and compare the diagnostic value of PET/CT and tumor markers. Results: In terms of specificity, the diagnostic value of PET/CT was lower than that of CEA (P < 0. 05) , and was not significantly different from that of other groups (P> 0. 05) . In terms of positive predictive value, there was no significant difference between PET/CT and tumor markers in each group (P> 0. 05) . Conclusion: 18F-FDG PET/CT has high sensitivity and tumor markers have higher specificity. Therefore, combining the two for comprehensive analysis can help improve the diagnostic confidence and accuracy of 18F-FDG PET/CT.

著录项

相似文献

  • 中文文献
  • 外文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号