Objective To study the value of Helicobacter pylori(H .pylori) stool antigen (HpSA)detection in patients after eradication of H .pylori .Methods A total of 170 patients from December 2011 to December 2013 in the First Hospital of Hebei Medical University underwent 14C urea breath test to detect HpSA ,observed sensitivity and accuracy of the HpSA detection .Results Patients after treatment of 1 week ,the sensitivity and accuracy of HpSA detection were 78 .08% and 68 .24% .Patients after treatment of 2 weeks ,the sensitivity and accuracy of HpSA de‐tection were74 .12% and 54 .71% .Patients after treatment of 3 weeks ,the sensitivity and accuracy of HpSA detection were 46 .38% and 47 .65% .Conclusion HpSA detection method with high accuracy ,high sensitivity ,high specificity for the diagnosis of Hp ,were suitable for children ,the elderly and the poor who are unable to carry out 13C or 14C‐u‐rea breath test ,and detection value is not affected by whether patients have accepted treated .%目的：探讨幽门螺杆菌（Hp）粪便抗原检测（HpSA）在Hp根除后患者中的效果，为Hp感染患者后期复查提供依据。方法选取该院2011年12月至2013年12月进行Hp根治后的170例患者进行研究，所有患者均进行14C尿素呼气试验检测HpSA，观察HpSA检测Hp的灵敏度和准确率，为Hp感染的检测提供依据。结果与14C尿素呼气试验金标准检测比较，患者治疗1周后，HpSA试验检测灵敏度为78．08％，诊断正确率为68．24％；患者治疗2周后HpSA试验检测灵敏度为74．12％，诊断正确率为54．71％；患者治疗3周后，HpSA试验检测灵敏度为46．38％，诊断正确率为47．65％。结论HpSA检测方法的诊断准确率高、灵敏度高、特异度高、适用于Hp的诊断，尤其适用于儿童、老年患者的筛查及无法开展13C或14C‐尿素呼气试验的贫困地区，且检测值不受患者是否进行治疗的影响。
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