目的：探讨血浆置换（PE）治疗急性重症有机磷农药中毒（ASOPP）的疗效。方法：将2011年1月－2014年5月收治的 ASOPP 患者62例随机分为对照组和研究组各31例，分别常规疗法和联合应用 PE 治疗，比较两组的临床疗效。结果：与对照组相比，研究组阿托品化、显著效果的时间和住院时间均明显缩短，中间综合征、反跳例数、死亡率均明显减少，治愈率明显增高，P均＜0．05。结论：在常规治疗的基础上联合 PE 治疗 ASOPP的抢救成功率高，死亡率低，并发症少。%Objective: To explore the effect of patients with acute severe organophosphorus pesticide poisoning (ASOPP) combined treatment with plasma exchange (PE). Methods: 62 patients with ASOPP from Jan 2011 to May 2014 were randomly divided into control group (n=31) and research group(n=31) treated by conventional therapy and combined PE based on the conventional therapy respectively. The clinical effects were compared between the two groups. Results: Compared with control group,atropinization time and hospitalization time were significantly shorter, intermediate syndrome,atropine rebound and mortality were significantly less, the cure rate was significantly higher in the research group,all P<0.05. Conclusion: There is a high successful rescue rate,few mortality and complications for patients with ASOPP treated by PE combined with conventional therapy.
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