The modification of nano-HAP with various biochemical methods such as fluorescein, rare earth doping, quantum dot notation is reviewed and the applications of such novel nano-HAP in bone tissue engineering, anti-cancer and drug carrier areas are mainly discussed. It is strongly believed that with the deeper research, the novel nano-HAP will make an exploitation and widely application in the near future.%介绍了各种生物化学方法如荧光素法、稀土元素掺杂法、量子点标记法等修饰纳米羟基磷灰石的技术,并着重阐述了生物化学修饰后的纳米羟基磷灰石在骨组织、抗肿瘤及药物载体方面的应用及其优势.相信随着研究的深入,对新型纳米羟基磷灰石性能的了解会越来越多,其用途也会越来越广泛.
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