Objective To observe the effect of Nicorandil Tablets treatment of coronary heart disease and chronic heart failure. Methods 80 cases of coronary heart disease patients with chronic heart failure as the basic research object, divide them into observation group and control group, 40 cases in each group. The control group take routine treatment, including ACE inhibitors, beta blockers, diuretics, digitalis, the observation group, on the basis of plus nicorandil. comparison of two groups of patients with heart function improvement, brain natriuretic peptide and cardiac color doppler ultrasound changes were analyzed and compared. Results Two groups of patients after treatment, the clinical effect of different degrees of improvement, The treatment effect of the observation group was significantly higher than that of the control group, the difference was statistically significant (P<0.05). Conclusion Using nicorandil on coronary heart disease in patients with chronic heart failure treatment, can reduce the patients psychological or physical pain and improve myocardial function in patients with heart failure.%目的：观察尼可地尔片治疗冠心病慢性心力衰竭的效果。方法80例冠心病慢性心力衰竭患者为基本研究对象，采取随机分成两组。将其分成观察组和对照组，各40例。对照组患者主要采取的常规治疗，其中包括ACEI、β受体阻滞剂、利尿剂、洋地黄。观察组，在基础上加用尼可地尔。对比两组患者的心功能改善、氨基末端前利钠肽值以及心脏彩超的变化进行分析比较。结果两组患者经过相对应的治疗后，临床效果均得到了不同程度上的改善，观察组患者的治疗效果明显高于对照组，差异具有统计学意义（P<0.05）。结论利用尼可地尔对冠心病慢性心力衰竭患者进行治疗，有利于减少患者的心理或生理上的痛苦，改善心衰患者的心肌功能。
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