Objective To explore effect and side effect of Gemcitabine combined with shenyi capsule on elderly advanced non-small cell lung cancel NSCLC ). Methods 27 patients received gemcitabine (1000mg/ m2 dl ,8 intravenous dripping,4 weeks ),and were given shenyi capsule meanwhile( 2 capsules per time,2 times per day ,4 weeks as one period ). Results All patients can sit for evaluation and there were 2 patients of CR,10 patients of PR,11 patients of SD,4 patients of PD. Total efficacy was 44.4% .clinical benefit rate 85. 1%. The major side effect were WBC and PLT decrease,but all within tolerance. Conclusion Gemcitabine combined with shenyi capsule has a good efficacy on elderly advanced NSCIX patients, can improve life quality,prolong surrival time,and all patients can endure the side effect.%目的 观察吉西他滨联合参一胶囊治疗老年晚期非小细胞肺癌(NSCLC)的疗效与不良反应.方法 对27例老年晚期NSCLC患者采用国产吉西他滨1000 mg/m2,第1、8天静脉滴注,4周方案.化疗同时服用参一胶囊每日2次,每次2粒,4周为1个疗程.结果 27例患者中完全缓解2例,部分缓解10例,稳定期11例,进展期4例.总有效率44.4%,临床受益率85.1%.不良反应以白细胞及血小板下降为主,均可耐受.结论 吉西他滨联合参一胶囊治疗老年晚期非小细胞肺癌疗效好,可明显改善生活质量,延长生存时间,不良反应轻,患者可耐受.
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