Objective:To explore the nursing of malignant syndrome neuroleptic induced by antipsychotic drugs. Methods:Clinical features of 44 cases with mental disease were analyzed retrospectively with the Levenson malignant syndrome diagnostic criteria and received supportive nursing. Results:44 cases of patients in the use of high potency antipsychotics appeared with the manifestations of fever,muscle tension,disturbance of consciousness,elevated serum cre-atine kinase and the plant nerve function disorder,obviously,with supportive care in early recognition and stop the medicine promptly and effectively,the dis-ease has been effictively controlled and mitigation. Conclusion:Require medication in patients with nursing staff to understand,especially in the process of the doctor treatment, medicine should focus on monitoring,strengthen the observation after medication. The early detection of abnormal situation timely with-drawal and supportive care,avoid to cause serious adverse reaction.%目的：：探讨不同抗精神病药物致神经阻滞剂恶性综合征的护理方法。方法：采用Levenson的恶性综合征诊断标准，对44例精神病患者的临床特征进行回顾性分析，在早期识别和及时停药后进行支持性护理。结果：44例患者在使用高效价抗精神病药物时出现以发热、肌张力增高、意识障碍、血清肌酸磷酸激酶升高以及植物神经功能紊乱等明显的临床表现，在治疗1~4周内，临床症状逐渐消失，病情得到有效控制和缓解。结论：要求护理人员了解患者用药情况，尤其在医师换药、调药的过程中应重点监护，加强患者服药后的观察。早期发现异常情况及时停药并给予支持性护理，避免造成严重不良反应的发生。
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