Objective To explore the platelet-rich plasma (PRP) application methods and applications value in burn. Methods The 66 deep Ⅱ degree burns patients were randomly divided into PRP group and control group;the control group received medication plus local dressing exchange,the PRP group received medication plus local dressing exchange and PRP external use. Then two groups were compared in granulation tissue maturity,wound healing time,serum concentrations of VEGF,serum concentrations of TGF-β1. Assessing the value of PRP in the treatment of burns was taken. Results PRP could significantly shorten the healing time of wounds;in PRP group at 5 d and 10 d after treatment,the maturity of granulation tissue were significantly greater than in the control group;in PRP group the concentration of VEGF and TGF-β1 in serum at 5 d and 10 d after treatment was significantly higher in the control group. Conclusion PRP has very significant effect and application value in the treatment of burns.%目的 探讨富血小板血浆(plateletrich plasma,PRP)在烧伤治疗中的应用方法和应用价值.方法将深Ⅱ度烧伤患者66例随机分为PRP组和对照组, 对照组采用内科治疗加局部换药,PRP组采用内科治疗加局部换药,并涂布PRP. 比较两组肉芽成熟程度、创伤愈合所需时间、血清中VEGF浓度、血清中TGF-β1浓度,评估PRP在烧伤治疗中的应用价值. 结果 PRP可以显著地缩短创伤愈合时间;PRP组在治疗5 d和10 d后创伤处肉芽组织成熟度显著大于对照组,患者血清中的VEGF和TGF-β1浓度显著高于对照组. 结论 PRP在烧伤治疗中具有显著的疗效和应用价值.
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