Objective:To observe efficacy of dexmedetomidine in preventing shivering after general anes-thesia for CABG surgery .Methods :Sixty patients scheduled for off-pump CABG surgery were randomized into dexmedetomidine group (calm with propofol and dexmedetomidine ,n=30) and control group (calm with propofol , n=30) .Observed the incidence of postoperative shivering and the classify grade of shivering .Observed the undulate of respiratory cycle index .Showed the difference between groups .Results:The patients in the control group showed a significantly higher postoperative incidence of shivering (46 .7% ) than those in dexmedetomidine group (13 .3% ) . The difference between groups on undulate of Respiratory cycle index had not statistically significant .Conclusion:Dexmedetomidine can lower the incidence of shivering after general anesthesia for CABG surgery and has no effect on respiratory cycle index .%目的：观察全麻非体外循环不停跳冠状动脉旁路移植术（CABG ）患者术后应用右美托咪定镇静对术后寒战的预防作用。方法：选取实施全麻非体外循环不停跳CABG手术的患者60例，随机分为观察组（术后应用丙泊酚联合右美托咪定镇静）和对照组（术后单纯使用丙泊酚镇静）各30例。观察术后寒战发生率、寒战分级及全麻清醒过程中（停用丙泊酚后）呼吸循环指标的波动；比较观察组与对照组脱离呼吸机过程的区别。结果：观察组术后寒战发生率13．3％，对照组发生率46．7％，两组差异有统计学意义，且对照组发生寒战的严重程度较高；两组患者术后监测的呼吸循环指标对比差异均无统计学意义。结论：全麻非体外循环不停跳CABG患者于术后应用右美托咪定静脉泵入可有效预防寒战发生，且对呼吸循环指标无影响。
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