Objective To observe the curative effect of interferon plus gamma globulin on children with infectious mono nucleosis( IM). Methods 90 patients with IM were divided into three groups randomly. The interferon alone( A group) ,interferon combined with ribaviri ( B group ) , and interferon plus gamma globulin ( C group) , then observed the change of symptoms and signs. Results The clinical symptoms and signs of the patients in the C group disappeared earlier than those in the A and B group ( P < 0.05 ). The total effective rate of each group was 89.7% 、56.0% and 80.8% , and C group of total effective rate was significant difference with A group (P<0.05 ). Conclusion Interferon plus gamma globulin is a safe and effective method for infectious mononucleosis, can raise the curative rate in children with IM.%目的 探讨3种不同药物组合治疗儿童传染性单核细胞增多症的临床疗效.方法 90例传染性单核细胞增多症患儿分为3组,选用干扰素(A组)、干扰素+病毒唑(B组)和干扰素+丙种球蛋白(C组)3种治疗方法.比较各组有效率、临床症状、体征的变化.结果 C组临床症状及体征均较A、B组消失快(P＜0.05)；3组有效率分别为89.7％、56.0％和80.8％,A组和C组有效率有统计学意义(P＜O.05).结论 应用干扰素联合丙种球蛋白治疗儿童传染性单核细胞增多症是一种安全、疗效确切的治疗方法,可以明显提高儿童传染性单核细胞增多症的治疗效果.
展开▼
