目的 探讨单侧球囊灌注小剂量骨水泥治疗重度骨质疏松椎体压缩性骨折的临床效果.方法 选择2009年2月至2015年2月收治的34例重度骨质疏松椎体压缩性骨折患者进行球囊扩张经皮椎体后凸成形术(PKP),根据术中骨水泥灌注量将患者分为小剂量组(骨水泥量为1.5～3ml)和常规剂量组(骨水泥量为3～6ml),将同期入院重度骨质疏松椎体压缩性骨折行保守治疗的患者设为对照组.结果 小剂量组和常规剂量组术后3d、术后6周、术后3个月、术后6个月疼痛目测类比评分明显优于对照组(P<0.05).小剂量组骨水泥渗漏率明显低于常规剂量组(P<0.05).结论 PKP治疗重度骨质疏松椎体压缩性骨折,术中灌注小剂量骨水泥能有效缓解疼痛,达到满意临床效果,并可明显减少骨水泥渗漏的发生.%Objective To explore the clinical effect of unipedicular percutaneous kyphoplasty with low dose bone cement in severe vertebral compressive fractures. Methods From February 2009 to February 2015,34 patients with severe vertebral compressive fractures were treated by percutaneous vertebroplasty. According to the dose of bone cement,the patients were divided into low dose group(1.5～3ml)and routine dose group (3～6ml). In addition,another patients who were hospitalized over the same period for severe vertebral compressive and treated by conservative treatment served as control group. Results The visual analogous scale score after surgery of the low dose group and routine dose group were significantly better than the control group(P<0.05). The bone cement leakage rate of the low dose group were also significantly lower than those in the routine dose group(P<0.05). Conclusion The PKP treated for severe vertebral compressive fractures with low dose bone cement can effective relief of pain, achieve satisfactory clinical effects,and effectively reduce the leakage of bone cement.
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