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首页> 外文期刊>Orthopedics >Unilateral versus bilateral balloon kyphoplasty in the treatment of osteoporotic vertebral compression fractures
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Unilateral versus bilateral balloon kyphoplasty in the treatment of osteoporotic vertebral compression fractures

机译：单侧或双侧球囊后凸成形术治疗骨质疏松性椎体压缩性骨折

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Bilateral and unilateral approaches are the main methods for balloon kyphoplasty. However, controversy exists about which leads to superior outcomes. The goal of this study was to compare the clinical effects and safety of unilateral vs bilateral balloon kyphoplasty for osteoporotic vertebral compression fractures. Five databases (PubMed, Cochrane Library, EMBASE, Web of Science, and Chinese Biomedical Database) were searched without language, publication, or date restrictions. Randomized controlled trials involving a total of 876 patients and comparing the efficacy of unilateral vs bilateral balloon kyphoplasty for osteoporotic vertebral compression fractures were identified. Meta-analysis revealed no significant differences in visual analog scale pain score up to 2-year follow-up (mean difference at 1 week, 0.17 [95% confidence interval (CI), -0.11 to 0.44]; mean difference at 1 year, 0.01 [95% CI, -0.29 to 0.32]; mean difference at 2 years, 0.28 [95% CI, -0.13 to 0.70]), Oswestry Disability Index pain score up to 1-year follow-up (mean difference at 1 week, 1.28 [95% CI, -2.62 to 5.17]; mean difference at 1 year, 1.87 (95% CI, -5.33 to 9.06]), anterior and middle vertebral height (mean difference anterior, -0.13 [95% CI, -0.32 to 0.06]; mean difference middle, -0.16 [95% CI, -0.36 to 0.03]), or kyphotic angle (mean difference, -0.02 [95% CI, -0.65 to 0.61]); however, the unilateral approach resulted in a shorter operative time (mean difference, -19.33 [95% CI, -4.42 to -14.24]), smaller amount of cement injected (mean difference, -2.07 [95% CI, -2.42 to -1.71]), and lower risk of cement leakage (mean difference, 0.47 [95% CI, 0.24-0.92]) than the bilateral approach. The unilateral approach resulted in pain relief and vertebral height and kyphotic angle restoration comparable with that of bilateral kyphoplasty. The unilateral approach should be considered an effective option for the treatment of osteoporotic vertebral compression fractures.
机译：双边和单侧方法是球囊后凸成形术的主要方法。但是，关于是否导致更好的结果存在争议。这项研究的目的是比较单侧与双侧球囊后凸成形术治疗骨质疏松性椎体压缩性骨折的临床效果和安全性。搜索了五个数据库（PubMed，Cochrane图书馆，EMBASE，Web of Science和中国生物医学数据库），而没有语言，出版物或日期限制。确定了一项涉及876名患者的随机对照试验，并比较了单侧与双侧球囊后凸成形术治疗骨质疏松性椎体压缩性骨折的疗效。荟萃分析显示，在长达2年的随访中，视觉模拟量表疼痛评分无明显差异（1周平均差异为0.17 [95％置信区间（CI），-0.11至0.44]; 1年平均差异， 0.01 [95％CI，-0.29至0.32]; 0.01 [95％CI，-0.29至0.32]; 2年时的平均差异; 0.28 [95％CI，-0.13至0.70]），Oswestry残疾指数疼痛评分，随访至1年（1周均值差异） ，1.28 [95％CI，-2.62至5.17]; 1年平均差1.87（95％CI，-5.33至9.06]），前，中椎骨高度（前平均差，-0.13 [95％CI，- 0.32到0.06];平均差中间值为-0.16 [95％CI，-0.36到0.03]）或后凸角（均值差为-0.02 [95％CI为-0.65到0.61]）;但是，采用了单侧方法在更短的手术时间内（平均差异为-19.33 [95％CI，-4.42至-14.24]），较小的水泥注射量（平均差异为-2.07 [95％CI，-2.42至-1.71]），并且更低水泥渗漏的风险（均值差异为0.47 [95％CI，0.24-0.92]） l方法。单侧入路可缓解疼痛，椎体高度和后凸角恢复与双侧后凸成形术相当。单侧入路应被认为是治疗骨质疏松性椎体压缩性骨折的有效选择。

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