Cannabinoids differentially modulate cortical information transmission through the sensorimotor or medial prefrontal basal ganglia circuits

机译：大麻素通过感觉运动或内侧前额叶基底神经节回路差异调节皮质信息传递

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Background and PurposeIn the sensorimotor (SM) and medial prefrontal (mPF) basal ganglia (BG) circuits, the cortical information is transferred to the substantia nigra pars reticulata (SNr) through the hyperdirect trans‐subthalamic pathway and through the direct and indirect trans‐striatal pathways. The cannabinoid CB1 receptor, which is highly expressed in both BG circuits, may participate in the regulation of motor and motivational behaviours. Here, we investigated the modulation of cortico‐nigral information transmission through the BG circuits by cannabinoids.

机译：背景和目的在感觉运动（SM）和内侧前额叶（mPF）基底神经节（BG）回路中，皮层信息通过超直接的跨丘脑下途径以及直接和间接的跨皮层途径转移至黑质网状组织（SNr）。纹状体途径。在两个BG回路中都高度表达的大麻素CB1受体可能参与运动和动机行为的调节。在这里，我们研究了大麻素通过BG电路对皮质-黑色信息传输的调制。

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期刊名称 British Journal of Pharmacology and Chemotherapy
作者
Mario Antonazzo; Amaia Gutierrez‐Ceballos; Irati Bustinza; Luisa Ugedo; Teresa Morera‐Herreras;
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作者单位

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年(卷),期 2019(176),8
年度 2019
页码 1156–1169
总页数 14
原文格式 PDF
正文语种
中图分类药学;
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专利

1. Cocaine-induced stereotypy is linked to an imbalance between the medial prefrontal and sensorimotor circuits of the basal ganglia. [J] . Aliane V, Perez S, Nieoullon The European Journal of Neuroscience . 2009,第7期

机译：可卡因引起的刻板印象与基底神经节的内侧前额叶和感觉运动回路之间的不平衡有关。
2. Distinct prefrontal top-down circuits differentially modulate sensorimotor behavior [J] . Rafiq Huda, Grayson O. Sipe, Vincent Breton-Provencher, Nature Communications . 2020,第1期

机译：独特的预偏压自上而下电路差异调制传感器行为
3. Integrated cannabinoid CB1 receptor transmission within the amygdala-prefrontal cortical pathway modulates neuronal plasticity and emotional memory encoding. [J] . Tan H, Lauzon NM, Bishop SF, Cerebral cortex . 2010,第6期

机译：杏仁核-前额叶皮层通路内整合的大麻素CB1受体传递调节神经元可塑性和情绪记忆编码。
4. Investigating Co-Activation between Medial Prefrontal and Primary Motor Cortical Spike Trains during Task Learning [C] . Shenghui Wu, Cunle Qian, Xiang Shen, IEEE International Conference on Systems, Man, and Cybernetics . 2020

机译：在任务学习期间调查内侧前额叶和初级运动皮质棘轮列车的共激活
5. Memory representation in the medial prefrontal cortex Cortical communication, and the development of a prefrontal ensemble code for associative memory. [D] . Morrissey, Mark. 2016

机译：内侧前额叶皮层皮质通讯中的记忆表示，以及用于关联记忆的前额综码的发展。
6. The orbital and medial prefrontal circuit through the primate basal ganglia [O] . SN Haber, K Kunishio, M Mizobuchi, 1995

机译：通过灵长类基底神经节的眶和内侧前额回
7. Integrated Cannabinoid CB1 Receptor Transmission within the Amygdala-Prefrontal Cortical Pathway Modulates Neuronal Plasticity and Emotional Memory Encoding [O] . H. Tan, N. M. Lauzon, S. F. Bishop, 2009

机译：Amygdala-prefortal皮质途径内的集成大麻素CB1受体透射调节神经元塑性和情绪记忆编码

Cannabinoids differentially modulate cortical information transmission through the sensorimotor or medial prefrontal basal ganglia circuits

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