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Complete genome sequence of the facultatively chemolithoautotrophic and methylotrophic alpha Proteobacterium Starkeya novella type strain (ATCC 8093T)

机译:兼性化能自养和甲基营养性α变形杆菌Starkeya Novella型菌株(ATCC 8093T)的完整基因组序列

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摘要

(Starkey 1934) Kelly et al. 2000 is a member of the family in the order ‘’, which is thus far poorly characterized at the genome level. Cultures from this species are most interesting due to their facultatively chemolithoautotrophic lifestyle, which allows them to both consume carbon dioxide and to produce it. This feature makes an interesting model organism for studying the genomic basis of regulatory networks required for the switch between consumption and production of carbon dioxide, a key component of the global carbon cycle. In addition, is of interest for its ability to grow on various inorganic sulfur compounds and several C1-compounds such as methanol. Besides , is only the second species in the family with a completely sequenced genome of a type strain. The current taxonomic classification of this group is in significant conflict with the 16S rRNA data. The genomic data indicate that the physiological capabilities of the organism might have been underestimated. The 4,765,023 bp long chromosome with its 4,511 protein-coding and 52 RNA genes was sequenced as part of the DOE Joint Genome Institute Community Sequencing Program (CSP) 2008.
机译:(Starkey 1934)Kelly等。 2000是''家族的一员,因此在基因组水平上迄今描述不清。来自该物种的培养物由于其兼性的化学自养型生活方式而最为有趣,这使它们既可以消耗二氧化碳也可以产生二氧化碳。此功能使模型生物成为有趣的模型生物,用于研究调节和消耗二氧化碳和二氧化碳之间的转换所需的调节网络的基因组基础,二氧化碳是全球碳循环的关键组成部分。另外,由于其能够在各种无机硫化合物和几种C1化合物(如甲醇)上生长的能力而引起人们的关注。此外,只是 家族中具有第二个完全分型菌株基因组的物种。该组的当前分类学分类与16S rRNA数据存在重大冲突。基因组数据表明该生物的生理能力可能被低估了。作为美国能源部联合基因组研究所社区测序计划(CSP)2008的一部分,对4,765,023 bp长的染色体及其4,511个蛋白质编码和52个RNA基因进行了测序。

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