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Complete genome sequence of the facultatively chemolithoautotrophic and methylotrophic alpha Proteobacterium Starkeya novella type strain (ATCC 8093T)

机译:兼性化学自养和甲基营养的α变形杆菌Starkeya Novella型菌株(ATCC 8093T)的完整基因组序列

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Starkeya novella (Starkey 1934) Kelly et al. 2000 is a member of the family Xanthobacteraceae in the order ‘Rhizobiales’, which is thus far poorly characterized at the genome level. Cultures from this species are most interesting due to their facultatively chemolithoautotrophic lifestyle, which allows them to both consume carbon dioxide and to produce it. This feature makes S. novella an interesting model organism for studying the genomic basis of regulatory networks required for the switch between consumption and production of carbon dioxide, a key component of the global carbon cycle. In addition, S. novella is of interest for its ability to grow on various inorganic sulfur compounds and several C1-compounds such as methanol. Besides Azorhizobium caulinodans, S. novella is only the second species in the family Xanthobacteraceae with a completely sequenced genome of a type strain. The current taxonomic classification of this group is in significant conflict with the 16S rRNA data. The genomic data indicate that the physiological capabilities of the organism might have been underestimated. The 4,765,023 bp long chromosome with its 4,511 protein-coding and 52 RNA genes was sequenced as part of the DOE Joint Genome Institute Community Sequencing Program (CSP) 2008.
机译:Starkeya Novella(Starkey 1934)Kelly等。 2000年是根瘤菌科的根瘤菌科的一员,因此在基因组水平上迄今表现不佳。来自该物种的培养物由于其兼性的化学自养型生活方式而最为有趣,这使它们既可以消耗二氧化碳也可以产生二氧化碳。这一特征使中叶链霉菌成为一种有趣的模型生物,用于研究在全球碳循环的关键组成部分即二氧化碳的消费和生产之间转换所需的调控网络的基因组基础。此外,新奇链球菌因其在各种无机硫化合物和几种C1化合物(例如甲醇)上的生长能力而受到关注。除了满江红假单胞菌外,中叶链球菌仅是Xanthobacteraceae科中第二个具有完整菌株基因组序列的物种。该组的当前分类学分类与16S rRNA数据存在重大冲突。基因组数据表明该生物的生理能力可能被低估了。作为DOE联合基因组研究所社区测序计划(CSP)2008的一部分,对4,765,023 bp长的染色体及其4,511个蛋白质编码和52个RNA基因进行了测序。

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