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Applying physical science techniques and CERN technology to an unsolved problem in radiation treatment for cancer: the multidisciplinary ‘VoxTox’ research programme

机译：将物理科学技术和CERN技术应用于癌症放射治疗中尚未解决的问题：多学科 VoxTox研究计划

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The VoxTox research programme has applied expertise from the physical sciences to the problem of radiotherapy toxicity, bringing together expertise from engineering, mathematics, high energy physics (including the Large Hadron Collider), medical physics and radiation oncology. In our initial cohort of 109 men treated with curative radiotherapy for prostate cancer, daily image guidance computed tomography (CT) scans have been used to calculate delivered dose to the rectum, as distinct from planned dose, using an automated approach. Clinical toxicity data have been collected, allowing us to address the hypothesis that delivered dose provides a better predictor of toxicity than planned dose.

机译：VoxTox研究计划将物理科学方面的专业知识应用于放射疗法毒性问题，汇集了工程，数学，高能物理（包括大型强子对撞机），医学物理学和放射肿瘤学方面的专业知识。在我们最初的109例接受根治性放射治疗的前列腺癌患者中，每日影像引导计算机断层扫描（CT）扫描已被用于通过自动方法来计算向直肠的输送剂量，与计划剂量不同。已经收集了临床毒性数据，这使我们可以解决以下假设：输送剂量比计划剂量可提供更好的毒性预测指标。

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期刊名称 other
作者
Neil G Burnet; Jessica E Scaife; Marina Romanchikova; Simon J Thomas; Amy M Bates; Emma Wong; David J Noble; Leila EA Shelley; Simon J Bond; Julia R Forman; Andrew CF Hoole; Gillian C Barnett; Frederic M Brochu; Michael PD Simmons; Raj Jena; Karl Harrison; Ping Lin Yeap; Amelia Drew; Emma Silvester; Patrick Elwood; Hannah Pullen; Andrew Sultana; Shannon YK Seah; Megan Z Wilson; Simon G Russell; Richard J Benson; Yvonne L Rimmer; Sarah J Jefferies; Nicolette Taku; Mark Gurnell; Andrew S Powlson; Carola-Bibiane Schönlieb; Xiaohao Cai; Michael PF Sutcliffe; Michael A Parker;
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年(卷),期 -1(1),1
年度 -1
页码 3–12
总页数 16
原文格式 PDF
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中图分类
关键词
Multidisciplinary physical sciences radiation toxicity;

机译：多学科;物理科学;辐射毒性;

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1. Helping learners in difficulty--the incidence and effectiveness of remedial programmes of the Medical Radiation Sciences Programme at University of Toronto and the Michener Institute for Applied Sciences, Toronto, Ontario, Canada. [J] . Szumacher E, Catton P, Jones GA, Annals of the Academy of Medicine, Singapore . 2007,第9期

机译：帮助有困难的学习者-多伦多大学和加拿大安大略省多伦多市米克纳应用科学学院的医学放射科学计划的补救计划的发生率和有效性。
2. Nonpharmacologic Approaches to Pain, Engorgement, and Plugging in Lactation: Applying Physical Therapy Techniques From Breast Cancer Care to Breastfeeding Patients [J] . Nicole Mogensen, Ada Portman, Katrina Mitchell Clinical lactation. . 2020,第1期

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机译：乳腺癌手术后的上肢疼痛的标准物理治疗计划没有额外的有益效果：随机对照试验
4. Generation Challenge Programme: the global effort to apply genomic sciences for the benefit of the resource poor [C] . Theo van Hintum European Association for Research on Plant Breeding General Congress . 2004

机译：一代挑战计划：全球努力适用基因组科学的利益差
5. Improved Pre-clinical Radiation Treatment Techniques for a Novel Mouse Model of Head-and-neck Cancer [D] . Chen, Deqi. 2019

机译：改进了临床前辐射处理技术，用于新型头颈癌小鼠模型
6. Regional multidisciplinary team intervention programme to improve colorectal cancer outcomes: study protocol for the Yorkshire Cancer Research Bowel Cancer Improvement Programme (YCR BCIP) [O] . John Taylor, Penny Wright, Hannah Rossington, 2019

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7. The Determination of Brick Provenance and Technology Using Analytical Techniques from the Physical Sciences. [O] . S. Pavía 2015

机译：利用物理科学分析技术确定砖的种源和技术。

Applying physical science techniques and CERN technology to an unsolved problem in radiation treatment for cancer: the multidisciplinary ‘VoxTox’ research programme

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