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Social-cognitive physiological and neural mechanisms underlying emotion regulation impairments: Understanding anxiety in autism spectrum disorder

机译:情绪调节障碍的社会认知生理和神经机制:了解自闭症谱系障碍中的焦虑

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摘要

Anxiety is one of the most common clinical problems among children, adolescents, and adults with autism spectrum disorder (ASD), yet we know little about its etiology in the context of ASD. We posit that emotion regulation (ER) impairments are a risk factor for anxiety in ASD. Specifically, we propose that one reason why anxiety disorders are so frequently comorbid with ASD is because ER impairments are ubiquitous to ASD, stemming from socio-cognitive, physiological, and neurological processes related to impaired cognitive control, regulatory processes, and arousal. In this review, we offer a developmental model of how ER impairments may arise in ASD, and when (moderating influences) and how (meditational mechanisms) they result in anxiety.
机译:焦虑症是自闭症谱系障碍(ASD)的儿童,青少年和成年人中最常见的临床问题之一,但我们对ASD的病因学知之甚少。我们认为情绪调节(ER)障碍是ASD焦虑的危险因素。具体而言,我们提出焦虑症如此频繁与ASD并存的原因之一是,ER障碍普遍存在于ASD中,其源于与认知控制,调节过程和唤醒受损有关的社会认知,生理和神经过程。在这篇综述中,我们提供了一个发展模型,说明ER障碍如何在ASD中发生,以及何时(缓解影响)以及它们如何导致(焦虑机制)焦虑。

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