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Interactions of HIV Other Sexually Transmitted Diseases and Genital Tract Inflammation Facilitating Local Pathogen Transmission and Acquisition

机译:HIV其他性传播疾病生殖道炎症促进当地病原体传播和采集的相互作用

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摘要

Despite several decades of clinical trials assessing the impact of etiological treatment of sexually transmitted diseases (STDs) to decrease HIV acquisition and transmission, almost all of these trials have not proven to be efficacious. Increasing evidence suggests that specific STD treatment alone may not be sufficient to alter the genital tract inflammatory milieu that is created by STDs. This paper examines the associations between STDs and HIV susceptibility and infectiousness, and considers the role of chronic and refractory inflammation to create an environment that potentiates HIV and STD transmission and acquisition by reviewing biological, observational, and clinical trial data.

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  • 期刊名称 other
  • 作者单位
  • 年(卷),期 -1(65),3
  • 年度 -1
  • 页码 308–316
  • 总页数 13
  • 原文格式 PDF
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