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Segment-specific association between plasma homocysteine and carotid artery intima-media thickness in the Framingham Heart Study

机译:血浆同型素与颈动脉内膜介质厚度的细胞特异性关联在Framingham心脏研究中的厚度

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摘要

BackgroundHigher plasma total homocysteine (tHcy) is an established risk factor for cardiovascular disease. The relation between tHcy and carotid artery intima-media thickness (IMT) at the internal carotid artery (ICA)/bulb-IMT and common carotid artery (CCA)-IMT has not been systematically examined. Since the ICA/bulb segment is more prone to plaque formation than the CCA segment, differential associations with tHcy at these sites might suggest mechanisms of tHcy action.

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