• 主题
高级搜索  >
历史搜索 清空历史
首页> 美国卫生研究院文献>Poultry Science >Effect of supplementation of a dairy-originated probiotic bacterium Propionibacterium freudenreichii subsp. freudenreichii on the cecal microbiome of turkeys challenged with multidrug-resistant Salmonella Heidelberg
【2h】

Effect of supplementation of a dairy-originated probiotic bacterium Propionibacterium freudenreichii subsp. freudenreichii on the cecal microbiome of turkeys challenged with multidrug-resistant Salmonella Heidelberg

机译：补充乳碱益生菌细菌促进弗拉德氏菌患者的影响。 FreudenreichiiTourkeys的Cecal Microbiome挑战多药抗性沙门氏菌海德堡

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A dairy-originated probiotic bacterium, Propionibacterium freudenreichii subsp. freudenreichii B3523 (PF) was found to be effective in reducing multidrug-resistant Salmonella Heidelberg (MDR SH) colonization in turkey poults (2-week-old) and growing (7-week-old) and finishing (12-week-old) turkeys. In this study, we explored the potential for microbiome modulation in the cecum of turkeys of different age groups due to PF supplementation in conjunction with MDR SH challenge. One-day-old commercial turkey poults were allocated to 3 treatment groups: negative control (N; turkeys without PF supplementation or SH challenge), SH control (S; turkeys challenged with SH without PF supplementation), and test group (P; turkeys supplemented with PF and challenged with SH). Turkeys were supplemented with 1010 CFU PF in 5-gallon (18.9 L) water until 7 or 12 week of age. At the 6th or 11th wk, turkeys were challenged with SH at 106 and 108 CFU/bird by crop gavage, respectively. After 2 and 7 d of challenge (2-d postinoculation [PI] and 7-d PI, respectively), cecal samples were collected and microbiome analysis was conducted using Illumina MiSeq. The experiments were repeated twice with 8 and 10 turkeys/group for 7- and 12-wk studies, respectively. Results indicated that the species richness and abundance (Shannon diversity index) was similar among the treatment groups. However, treatments caused apparent clustering of the samples among each other (P < 0.05). Firmicutes was the predominant phylum in the growing and finishing turkey cecum which was evenly distributed among the treatments except on wk 12 where the relative abundance of Firmicutes was significantly higher in P than in N (P = 0.02). The MDR SH challenge resulted in modulation of microflora such as Streptococcus, Gordonibacter, and Turicibacter (P < 0.05) in the S groups compared with the P and N groups, known to be associated with inflammatory responses in birds and mammals. The supplementation of PF increased the relative abundance of carbohydrate-fermenting and short-chain fatty acid–producing genera in the P group compared with the S group (P < 0.05). Moreover, the results revealed that PF supplementation potentially modulated the beneficial microbiota in the P group, which could mitigate SH carriage in turkeys.
机译：乳制品起源的益生菌细菌，Propionibibactiumsfreudenreichii子公司。发现FreudenReichii B3523（PF）有效地减少了在土耳其Poults（2周龄）的多药抗性沙门氏菌（MDR SH）殖民地（2周龄）和生长（7周龄）和整理（12周龄）火鸡。在这项研究中，由于PF补充与MDR SH挑战结合，我们探讨了不同年龄组的火鸡盲肠的微生物组调制潜力。一天历史的商业土耳其泥浆分配给3种治疗组：阴性对照（N; Turkeys没有PF补充或Sh挑战），SH控制（S; Turkeys用SH挑战没有PF补充）和测试组（P; Turkeys补充有PF并用SH挑战）。 Turkeys在5加仑（18.9升）水中补充了1010个CFU PF，直至年龄的7周或12周。在第6或第11周，Turkeys分别通过作物饲养分别在106和108 CFU /鸟类上用SH挑战。在2和7 d挑战之后（分别为2-D开采[pi]和7-d pi），收集了Cechal样品，使用Illumina miseq进行微生物组分析。将实验重复两次，分别用8和10个火鸡/组重复两次，可分别进行7和12-WK研究。结果表明，物种丰富性和丰富（Shannon多样性指数）在治疗组中相似。然而，治疗导致样品的明显聚类相互含量（P <0.05）。 FARMICUSTS是生长和整理的土耳其盲肠中的主要场，除了WK 12之外的治疗中均匀分布，其中对P的相对丰度显着高于N（P = 0.02）。与P和N基团相比，MDR SH挑战导致S群中的微氟氯脲如链球菌，戈尔多组和Turoicibacter（P <0.05），已知与鸟类和哺乳动物中的炎症反应相关。与S组相比，PF的补充增加了P组中的碳水化合物发酵和短链脂肪酸的产量的相对丰度（P <0.05）。此外，结果表明，PF补充潜在地调节P组中的有益微生物群，这可能会在火鸡中减轻静电。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号