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Anaphylactoid reaction to immunoadsorptive membrane in a patient with myasthenia gravis

机译:重症肌无力患者对免疫吸附膜的类过敏反应

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Extracorporeal adsorption therapy has been carried out clinically in cases of myasthenia gravis (MG) since the 1980s without any major complications. Despite a lack of clinical evidence, it has been accepted as a potential therapy for steroid-resistant patients in many institutes. Recently, we experienced a case of MG with an anaphylactoid reaction during extracorporeal immunoadsorption therapy. A 64 year old women with MG showed an anaphylactoid reaction immediately after the initiation of adsorption therapy using a polyvinylalcohol gel column. It is therefore important to bear in mind that extracorporeal adsorption therapy could trigger an anaphylactoid reaction, which may induce a MG crisis.
机译:自1980年代以来,临床上已在重症肌无力(MG)病例中进行了体外吸附疗法,没有任何重大并发症。尽管缺乏临床证据,但在许多机构中,它已被视为对类固醇耐药患者的潜在疗法。最近,我们在体外免疫吸附治疗期间发生了一起MG,发生过敏性反应。一位64岁的MG妇女在开始使用聚乙烯醇凝胶柱进行吸附治疗后立即出现类过敏反应。因此,重要的是要牢记体外吸附疗法可能会引发类过敏反应,从而引发MG危机。

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