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Emotion regulation individual therapy for adolescents with nonsuicidal self-injury disorder: a feasibility study

机译:情绪调节个体治疗非自杀性自残青少年的可行性研究

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Nonsuicidal self-injury (NSSI) is a serious health risk behavior that forms the basis of a tentative diagnosis in DSM-5, NSSI Disorder (NSSID). To date, established treatments specific to NSSI or NSSID are scarce. As a first step in evaluating the feasibility, acceptability, and utility of a novel treatment for adolescents with NSSID, we conducted an open trial of emotion regulation individual therapy for adolescents (ERITA): a 12-week, behavioral treatment aimed at directly targeting both NSSI and its proposed underlying mechanism of emotion regulation difficulties. Seventeen girls (aged 13–17; mean?=?15.31) with NSSID were enrolled in a study adopting an uncontrolled open trial design with self-report and clinician-rated assessments of NSSI and other self-destructive behaviors, emotion regulation difficulties, borderline personality features, and global functioning administered at pre-treatment, post-treatment, and 6-month follow-up. Measures of NSSI and emotion regulation difficulties were also administered weekly during treatment. Ratings of treatment credibility and expectancy and the treatment completion rate (88%) were satisfactory, and both therapeutic alliance and treatment attendance were strong. Intent-to-treat analyses revealed significant improvements associated with large effect sizes in past-month NSSI frequency, emotion regulation difficulties, self-destructive behaviors, and global functioning, as well as a medium effect size in past-month NSSI versatility, from pre- to post-treatment. Further, all of these improvements were either maintained or further improved upon at 6-month follow-up. Finally, change in emotion regulation difficulties mediated improvements in NSSI over the course of treatment. Results suggest the acceptability, feasibility, and utility of this treatment for adolescents with NSSID. ClinicalTrials.gov (NCT02326012, December 22, 2014, retrospectively registered).
机译:非自杀性自残(NSSI)是一种严重的健康风险行为,构成DSM-5,NSSI障碍(NSSID)暂定诊断的基础。迄今为止,尚缺乏针对NSSI或NSSID的既定治疗方法。作为评估针对NSSID的青少年新疗法的可行性,可接受性和实用性的第一步,我们进行了一项针对青少年的情绪调节个体疗法(ERITA)的公开试验:一项为期12周的行为治疗,旨在直接针对两种NSSI及其提议的情绪调节困难的潜在机制。一项采用非对照开放试验设计的研究纳入了一项研究,该研究采用NSSID的17名女孩(13至17岁;平均数== 15.31),该研究采用自我报告和临床医师评估的NSSI和其他自我破坏行为,情绪调节困难,界限分明的方法在治疗前,治疗后和6个月的随访中进行个性化特征和总体功能管理。在治疗期间,每周还对NSSI和情绪调节困难进行测量。治疗可信度和期望值以及治疗完成率(88%)令人满意,治疗联盟和治疗出席率均很高。意向性治疗分析显示,与前一个月的NSSI频率,情绪调节困难,自我毁灭行为和整体功能以及前一个月的NSSI多功能性的中等影响大小相比,前一个月的NSSI频率影响范围大,显着改善。 -进行后处理。此外,在6个月的随访中,所有这些改善都得以维持或进一步改善。最后,情绪调节困难的改变介导了在治疗过程中NSSI的改善。结果表明该治疗对NSSID青少年的可接受性,可行性和实用性。 ClinicalTrials.gov(NCT02326012,2014年12月22日,追溯注册)。

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