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首页> 外文期刊>Case Reports in Obstetrics and Gynecology >Malignant Transformation of a Mature Cystic Ovarian Teratoma into Thyroid Carcinoma, Mucinous Adenocarcinoma, and Strumal Carcinoid: A Case Report and Literature Review
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Malignant Transformation of a Mature Cystic Ovarian Teratoma into Thyroid Carcinoma, Mucinous Adenocarcinoma, and Strumal Carcinoid: A Case Report and Literature Review

机译：一个成熟的囊性卵巢畸胎瘤恶性转化为甲状腺癌，粘液腺癌和粒状类癌的病例报告和文献复习

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Malignant transformation of a mature cystic teratoma (MCT) is an infrequent, often asymptomatic event. We report the first example of a struma ovarii with a focus of follicular variant of papillary thyroid carcinoma (a), mucinous adenocarcinoma (b), and strumal carcinoid tumor (c)—all three arising in one mature cystic teratoma of the ovary. From our reviews, we found limited data to guide management when these malignant foci occur within an MCT. Consideration should be given to thyroidectomy followed by total-body scanning and serum studies for foci of thyroid carcinoma and adjuvant therapy with thyroidectomy and radioablation if residual disease is identified (a). Additionally, extrapolating from data for mucinous adenocarcinomas, consideration could be given to adjuvant chemotherapy after appropriate staging (b). Strumal carcinoid tumors should be treated as tumors of low malignant potential. Observation is appropriate if after complete staging, no invasive implants are noted (c).
机译：成熟的囊性畸胎瘤（MCT）的恶性转化是罕见的，通常无症状的事件。我们报道了第一个卵巢畸形灶，其卵泡变型为乳头状甲状腺癌（a），粘液腺癌（b）和基质类癌（c），这三个例子均发生在一个卵巢成熟的囊性畸胎瘤中。从我们的评论中，我们发现，当这些恶性灶发生在MCT内时，有限的数据可以指导治疗。应考虑甲状腺切除术，然后进行全身扫描和血清研究以了解甲状腺癌的病灶，并在发现残留疾病的情况下辅以甲状腺切除术和放射消融的辅助治疗（a）。另外，从粘液腺癌的数据推断，在适当的分期后可以考虑辅助化疗（b）。角质类癌应视为恶性程度低的肿瘤。如果在分期完成后未发现有创植入物，则观察是适当的（c）。

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