...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Case Reports in Obstetrics and Gynecology >Pemphigoid Gestationis after Spontaneous Expulsion of a Massive Complete Hydatidiform Mole
【24h】

Pemphigoid Gestationis after Spontaneous Expulsion of a Massive Complete Hydatidiform Mole

机译：天性完全葡萄胎完全驱除后的天疱疮妊娠

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Pemphigoid gestationis (PG) is a rare, perinatal, autoimmune, and blistering dermatosis. Only few cases of PG involving hydatidiform moles have been reported. Complete hydatidiform moles are usually evacuated by dilatation and curettage. We report a patient with a massive complete hydatidiform mole that underwent spontaneous expulsion; she subsequently developed PG. A 19-year-old unmarried nulligravid woman was referred to our hospital following excessive vaginal bleeding after an uncertain amenorrheal period. The patient presented with preshock vital signs, severe anemia, and a positive urine pregnancy test. Imaging examinations revealed a massive intrauterine mass (19 × 15 × 10 cm), suggesting a complete hydatidiform mole. She was hospitalized and treated with blood transfusion. Sixteen hours after hospitalization, the massive molar mass underwent spontaneous expulsion and bleeding ceased. Three days after the expulsion, she developed pruritic skin lesions including papules, erythemas, and bullae, which spread over her entire body. Skin biopsy revealed PG and subepidermal blister formation and linear complement C3 deposition along the basement membrane zone, and the serum anti-BP180 antibody level was found to be high on measurement. She was effectively treated with 50 mg/day of oral prednisolone. Her skin lesions disappeared, leaving pigmentation.
机译：天疱疮妊娠（PG）是一种罕见的围产期自身免疫性水疱性皮肤病。仅报道了几例涉及葡萄胎的PG。完整的葡萄胎通常通过扩张和刮除术来排空。我们报告了一名患者，患者有大量完全的葡萄胎，并已自然排出。她随后开发了PG。不确定的闭经期后，阴道流血过多，一名19岁未婚零重力妇女被转诊到我们医院。该患者表现出震前生命体征，严重贫血和尿液妊娠试验阳性。影像学检查发现子宫内有大量肿块（19×15×10 cm），提示葡萄胎完整。她住院并接受输血治疗。住院十六小时后，巨大的磨牙团被自然排出，并且止血。驱逐出境三天后，她出现了瘙痒性皮肤病变，包括丘疹，红斑和大疱，遍布整个身体。皮肤活检显示PG和表皮下水疱形成以及沿基底膜区域的线性补体C3沉积，并且测量发现血清抗BP180抗体水平较高。每天口服50毫克泼尼松龙可以有效治疗她。她的皮肤病变消失，留下色素沉着。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号