Acquired Amegakaryocytic Thrombocytopenia Purpura in a Rhesus Macaque (Macaca mulatta)

Hanley; Patrick W; nbsp; Baze; Wallace B; nbsp; McArthur; Mark J; nbsp; Bernacky; Bruce J; nbsp; Wilkerson; Greg K; nbsp; Barnhart; Kirstin F

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Acquired Amegakaryocytic Thrombocytopenia Purpura in a Rhesus Macaque (Macaca mulatta)

机译：猕猴（猕猴）获得的巨核细胞性血小板减少性紫癜

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A10-y-oldmultiparousrhesusmacaquepresentedforanannualroutinephysicalexamination.Clinically,theanimalhadpalemucousmembranes,petechialandecchymotichemorrhagesinmultiplesites,andalacerationatthetailbase.Severepancytopeniawasnotedonhematologicevaluation.ThemonkeywasseronegativeforSIV,simianT-lymphotropicvirus,simianretrovirustypeD,andMacacineherpesvirus1.Bonemarrowevaluationrevealedapaucityofmegakaryocyticprecursorsinahypercellularmarrowwithmarkederythroidhyperplasia.Inlightofthesefindings,thediagnosiswasacquiredamegakaryocyticthrombocytopeniapurpura.Duetothepoorprognosisofthesyndromeandclinicaldeteriorationofthemonkey,euthanasiawaselected.Adefinitivecauseofthethrombocytopeniawasnotidentified;however,thesyndromemayhavedevelopedsecondarytoarecentspontaneousabortion.Toourknowledge,thiscaserepresentsthefirstreportedobservationofacquiredamegakaryocyticthrombocytopeniapurpurainarhesusmonkey.

机译：A10-Y-oldmultiparousrhesusmacaquepresentedforanannualroutinephysicalexamination.Clinically，theanimalhadpalemucousmembranes，petechialandecchymotichemorrhagesinmultiplesites，andalacerationatthetailbase.Severepancytopeniawasnotedonhematologicevaluation.ThemonkeywasseronegativeforSIV，simianT-lymphotropicvirus，simianretrovirustypeD，andMacacineherpesvirus1.Bonemarrowevaluationrevealedapaucityofmegakaryocyticprecursorsinahypercellularmarrowwithmarkederythroidhyperplasia.Inlightofthesefindings，thediagnosiswasacquiredamegakaryocyticthrombocytopeniapurpura.Duetothepoorprognosisofthesyndromeandclinicaldeteriorationofthemonkey，euthanasiawaselected.Adefinitivecauseofthethrombocytopeniawasnotidentified;然而，thesyndromemayhavedevelopedsecondarytoarecentspontaneousabortion.Toourknowledge，thiscaserepresentsthefirstreportedobservationofacquiredamegakaryocyticthrombocytopeniapurpurainarhesusmonkey。

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《Comparative Medicine》 |2012年第3期|共页
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Hanley; Patrick W; nbsp; Baze; Wallace B; nbsp; McArthur; Mark J; nbsp; Bernacky; Bruce J; nbsp; Wilkerson; Greg K; nbsp; Barnhart; Kirstin F;
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中图分类畜牧、动物医学、狩猎、蚕、蜂;
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1. Acquired amegakaryocytic thrombocytopenia purpura in a rhesus macaque (Macaca mulatta). [J] . Hanley P. W., Baze W. B., McArthur M. J., Comparative Medicine . 2012,第3期

机译：猕猴（猕猴）中获得的巨核细胞性血小板减少性紫癜。
2. Birth of Rhesus Macaque (Macaca mulatta) Infants After In Vitro Fertilization and Gestation in Female Rhesus or Pigtailed (Macaca nemestrina) Macaques [J] . Kubisch HM, Ratterree M, Williams V, Comparative Medicine . 2005,第2期

机译：猕猴或猪尾猕猴体外受精和妊娠后恒河猴（猕猴）的出生
3. Birth of Rhesus Macaque (Macaca mulatta) Infants After In Vitro Fertilization and Gestation in Female Rhesus or Pigtailed (Macaca nemestrina) Macaques [J] . Kubisch, H. Michael, nbsp, Comparative Medicine . 2005,第2期

机译：猕猴或猪尾猕猴体外受精和妊娠后恒河猴（Macaca mulatta）婴儿的出生
4. Retinal functional and morphological comparisons of two different macaque species, Macaca mulatta and Macaca fasicularis, for models of laser eye injury [C] . Cheryl D. DiCarlo, Henry D. Hacker, Araceli Brown, Photonic Therapeutics and Diagnostics; Progress in Biomedical Optics and Imaging; vol.6, no.1 . 2005

机译：两种不同猕猴，猕猴和短尾猕猴的视网膜功能和形态学比较，用于激光眼损伤模型
5. Pathogenesis of acquired cytopenias in simian betaretrovirus (SRV) infection of rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques [D] . Montiel, Nestor A. 2008

机译：猕猴（猕猴）和猕猴（猕猴）猕猴猿猴逆转录病毒（SRV）感染中获得性血细胞减少的发病机理
6. Acquired Amegakaryocytic Thrombocytopenia Purpura in a Rhesus Macaque (Macaca mulatta) [O] . Patrick W Hanley, Wallace B Baze, Mark J McArthur, 2012

机译：猕猴（猕猴）获得的巨核细胞性血小板减少性紫癜
7. Shigella flexneri infection in a newly acquired rhesus macaque (Macaca mulatta) [O] . Lee, Jae-Il, Kim, Sang-Joon, Park, Chung-Gyu 2011

机译：新获得的恒河猴（猕猴）的志贺氏菌感染

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Acquired Amegakaryocytic Thrombocytopenia Purpura in a Rhesus Macaque (Macaca mulatta)

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