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Modeling of the controlled release of betacarotene into anhydrous ethanol from microcapsules

机译:从微胶囊向无水乙醇中β-胡萝卜素控释的建模

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In this paper several models of the mass transfer process are described with the aim of simulating the release of active principles from matrix-type polymeric microcapsules. The following mathematical models, which are available in the literature, are applied in this study: Fick's second law (CDMASSA), the linear drive force (LDF), an analytical model and other semi-empirical models. The release of the active principle (betacarotene) contained in microcapsules (PHBV) into a solvent (ethanol) was investigated. It was observed that the model obtained with Fick's second law provided a better fit with the literature data compared with the LDF model, the analytical model and the semi-empirical models. It can be concluded from this finding that the most complete model, based on the phenomenology of the problem, provided the best result. Highlights ? Study the suggested models and analyze what is the most appropriate for each case study. ? Evaluating prediction errors obtained through different models, using statistical tools. ? Discuss the different phenomenological approaches of experiments and models, because different parameters are involved.
机译:本文描述了传质过程的几种模型,目的是模拟活性成分从基质型聚合物微胶囊中的释放。在这项研究中应用了以下文献中可用的数学模型:菲克第二定律(CDMASSA),线性驱动力(LDF),分析模型和其他半经验模型。研究了微胶囊(PHBV)中所含的活性成分(β-胡萝卜素)向溶剂(乙醇)的释放。观察到,与LDF模型,分析模型和半经验模型相比,使用Fick第二定律获得的模型更适合文献数据。从该发现可以得出结论,基于问题现象学的最完整模型提供了最佳结果。强调 ?研究建议的模型并分析最适合每个案例研究的模型。 ?使用统计工具评估通过不同模型获得的预测误差。 ?讨论实验和模型的不同现象学方法,因为涉及不同的参数。

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