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首页> 外文期刊>International Journal of Pharmaceutical Sciences and Research >STUDY ON SAFETY AND EFFICACY OF DIFFERENT MODALITIES IN THE POST-OPERATIVE PAIN MANAGEMENT IN A TERTIARY CARE TEACHING HOSPITAL
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STUDY ON SAFETY AND EFFICACY OF DIFFERENT MODALITIES IN THE POST-OPERATIVE PAIN MANAGEMENT IN A TERTIARY CARE TEACHING HOSPITAL

机译：三级教学医院术后疼痛管理中不同方式的安全性和有效性研究

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ABSTRACT: Background: Postoperative pain control is an important part of effective postoperative care. However, 30 – 80% of postoperative patients complain about moderate to severe post-surgical pain as a result of the surgical procedure or a pre-existing disease. Aim: To assess the safety and efficacy of different modalities of postoperative pain management in post surgical wards of a tertiary care hospital. Method: It’s a prospective study was conducted in 213 patients of either gender, aged between 18 – 65 years. Patients were followed up from surgery till discharge or till the 4th postoperative day, the drugs given for pain relief both as single drug and combination drugs and adverse effects were monitored. The severity of pain was assessed using a numeric pain rating scale after 1 h of surgery, then followed by 2 h, 4 h, 6 h, 12 h, 24 h, 48 h and 96 h. Patient satisfaction with the analgesic therapy given was recorded at the time of discharge or after 4th postoperative day using 5 point Likert’s Scale. The data collected were tabulated and analyzed statistically using SPSS.16 software. Results: On comparing the various modalities of pain management, the combination therapy was found to be more effective than the single drug modality, as significant reduction in pain score was seen at 6th, 12th, 24th and 48th h with a p-value < 0.05. Conclusion: All the modalities used for postoperative pain management were safe and effective. The multimodal analgesic therapy for postoperative pain was more effective than the single modal analgesic therapy.
机译：摘要：背景：术后疼痛的控制是有效的术后护理的重要组成部分。但是，有30％至80％的术后患者抱怨由于手术过程或先前存在的疾病而导致中等至严重的术后疼痛。目的：评估三级医院手术后病房中不同方式术后疼痛管理的安全性和有效性。方法：这是一项前瞻性研究，研究对象为年龄在18至65岁之间的213名男女患者。对患者进行手术直至出院或术后第四天的随访，监测止痛药（单药和联合用药）及不良反应。术后1小时，然后使用2小时，4小时，6小时，12小时，24小时，48小时和96小时，使用数字疼痛等级量表评估疼痛的严重程度。在出院时或术后第4天后使用5点Likert量表记录患者对镇痛治疗的满意度。使用SPSS.16软件将收集的数据制成表格并进行统计分析。结果：在比较各种疼痛管理方式时，发现联合疗法比单一药物疗法更有效，因为疼痛评分在第6、12和12时显着降低，第24 和第48 h，p值<0.05。结论：所有用于术后疼痛处理的方法都是安全有效的。术后疼痛的多模式镇痛治疗比单模式镇痛治疗更有效。

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