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首页> 外文期刊>Iranian Journal of Reproductive Medicine >ANTI-MULLERIAN HORMONE AS A PREDICTOR OF OVARIAN RESERVE AND OVARIAN RESPONSE IN IVF WOMEN FROM GAZA STRIP
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ANTI-MULLERIAN HORMONE AS A PREDICTOR OF OVARIAN RESERVE AND OVARIAN RESPONSE IN IVF WOMEN FROM GAZA STRIP

机译：抗苗勒管激素作为加沙地带试管婴儿中卵巢储备和卵巢反应的预测指标

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Background: Careful evaluation of patients and proper treatment with right techniques are essential for successful outcome of assisted reproduction. To obtain satisfactory results, it is necessary to assess ovarian reserve before planning treatment.Objective: To evaluate anti-mullerian hormone as a predictor of fertility potential in terms of ovarian reserve and ovarian response reflected by antral follicles and mature oocyte counts in response to menotrophin stimulation in in vitro fertilization (IVF) women from Gaza Strip.Materials and Methods: This prospective cohort study consisted of 81 women (mean age 28.7 years) attending IVF at Al-Basma Fertility Center in Gaza City. Blood withdrawal for antimullerian hormone measurement was performed in all the patients and the number of oocytes and embryos were recorded.Results: The total number of retrieved oocytes was inversely associated with age (12.5?±4.5, 11.0?±5.4 and 6.9?±4.7 at age ?￡25, 26-35 and 35 years, respectively (F=4.793 and p=0.011). The ovarian response to Menotrophin (FSH 75IU, LH 75 IU) stimulation was better for younger age. There was a significant positive association between ovarian response in terms of total number of oocytes and antimullerian hormone levels. The maximum level of antimullerian hormone was observed in females who achieved positive pregnancies (4.5?±2.5 ng/mL) followed by negative pregnancies (2.9?±1.8 ng/mL) with significant differences (F=6.862 and p=0.002). Correlation coefficient revealed that the number of mature oocytes showed strong positive correlation with the antimullerian hormone levels (r=0.469, p=0.001).Conclusion: Anti-mullerian hormone can be used in IVF programs as a good predictor of ovarian reserve and ovarian response.
机译：背景：对患者进行仔细评估并用正确的技术进行正确治疗对于辅助生殖的成功结果至关重要。为了获得满意的结果，有必要在计划治疗之前评估卵巢储备。目的：根据卵巢储备和由卵泡反射的卵巢反应和对卵磷脂的成熟卵母细胞计数来评估抗苗勒激素作为生育潜力的预测指标材料和方法：这项前瞻性队列研究由81名在加沙市Al-Basma生育中心接受IVF的妇女（平均年龄28.7岁）组成。所有患者均抽血进行抗苗勒激素测定，并记录卵母细胞和胚胎数目。结果：回收的卵母细胞总数与年龄成反比（12.5±4.5、11.0±5.4和6.9±4.7）分别在年龄≥25岁，26-35岁和> 35岁时（F = 4.793和p = 0.011），卵巢对促性腺激素（FSH 75IU，LH 75 IU）刺激的反应在年轻时较好。卵巢反应与卵母细胞总数和抗苗勒管激素水平之间的相关性。妊娠阳性（4.5？±2.5​​ ng / mL）继之以阴性妊娠（2.9？±1.8 ng / mL）的女性观察到最大抗苗勒激素水平mL）差异有统计学意义（F = 6.862和p = 0.002），相关系数显示，成熟的卵母细胞数量与抗苗勒激素水平呈强正相关（r = 0.469，p = 0.001）。在IVF pro中使用克可以很好地预测卵巢储备和卵巢反应。

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