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Cadmium Induced Toxicity and Antioxidant Activities in Labeo Rohita (Hamilton)

机译：镉对Labeo Rohita（汉密尔顿）的毒性和抗氧化活性

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The present study was carried out to observe the toxicity of cadmium at various sublethal concentrations in common edible fish, Labeo rohita (rohu) during various exposure periods. Labeo rohita was exposed to sublethal concentrations of cadmium chloride that is 1.0 mg l-1, 1.5 mg l-1 and 2.0 mg l-1 along with control for 24hr, 48hr, 72hr and 96hr. The fishes were sacrificed and muscle was collected for the estimation of total proteins, carbohydrate, lipids and antioxidant enzymes i.e. superoxide dismutase (SOD), lipid peroxidation (LPO) and catalase (CAT) activities. The maximum decrease in protein, carbohydrate and lipid content were found to be 40.44%, 32.17% , 33.12% at 96hr of exposure at 2 mg l-1 of CdCl2. Antioxidant enzyme activities were increased when fish exposed to sublethal concentration of cadmium chloride. The maximum increase in the level of catalase, lipid peroxidation, and superoxide dismutase was noted to be 141.2%, 94.6% and 71% respectively at 96hr exposure for 2.0 mg l-1 of Cdcl2.The results revealed that cadmium is highly toxic in muscle of Labeo rohita as there was a drastic reduction of biochemical parameters (carbohydrate, protein, lipids) and changes in the level of antioxidant enzymes activities.
机译：进行本研究以观察不同暴露水平下普通食用鱼Labeo rohita（rohu）中不同致死浓度的镉的毒性。 Labeo rohita暴露于亚致死浓度的氯化镉，分别为1.0 mg l -1 ，1.5 mg l -1 和2.0 mg l -1 以及控制24小时，48小时，72小时和96小时。处死鱼并收集肌肉以估计总蛋白质，碳水化合物，脂质和抗氧化酶，即超氧化物歧化酶（SOD），脂质过氧化（LPO）和过氧化氢酶（CAT）活性。在2 mg l -1 CdCl 2 暴露96小时后，蛋白质，碳水化合物和脂质含量的最大减少量分别为40.44％，32.17％和33.12％。当鱼暴露于亚致死浓度的氯化镉中时，抗氧化酶活性增加。在2.0 mg l -1 的Cdcl 2暴露96小时后，过氧化氢酶，脂质过氧化和超氧化物歧化酶的最大增加分别为141.2％，94.6％和71％。 。结果表明，镉在Labeo rohita的肌肉中具有剧毒作用，这是因为生化参数（碳水化合物，蛋白质，脂质）的急剧降低以及抗氧化酶活性水平的变化。

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