H19: a long non-coding RNA with different roles in cancer progression

Mohammadreza Hajjari

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H19: a long non-coding RNA with different roles in cancer progression

机译：H19：长的非编码RNA在癌症进展中具有不同的作用

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Long non-coding RNAs (lncRNAs) are pervasively transcribed and critical RNA molecules with different roles in the cell. The association of some lncRNAs with different diseases especially cancers has been documented. One of these lncRNAs is H19 which its dysregulation is reported in different cancers. In this review, we describe the molecular function and regulation of H19 in human cells. We also point to the H19 dysregulation in different types of cancer.

机译：长的非编码RNA（lncRNA）被普遍转录，并且在细胞中具有不同作用的关键RNA分子。一些lncRNA与不同疾病，尤其是癌症的关联已有文献记载。这些lncRNA之一是H19，据报道在不同的癌症中其失调。在这篇综述中，我们描述了人类细胞中H19的分子功能和调控。我们还指出了不同类型癌症中的H19失调。

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《Gene Therapy and Molecular Biology》 |2014年第9期|共10页
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Mohammadreza Hajjari;
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中图分类基础医学;
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机译：H19 Long非编码RNA在癌症发生，进展和转移中的作用-提出的统一理论

H19: a long non-coding RNA with different roles in cancer progression

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