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首页> 外文期刊>Fiziologia: official journal of the Romanian Society of Physiological Sciences >NEUROPHYSIOLOGICAL AND NEUROPSYCHOLOGICALANALYSIS OF COGNITION IN NEWHYPOTHYROID FEMALES
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NEUROPHYSIOLOGICAL AND NEUROPSYCHOLOGICALANALYSIS OF COGNITION IN NEWHYPOTHYROID FEMALES

机译：甲状旁腺激素的神经生理学和神经生理学分析

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摘要

Hypothyroidism is a common thyroid disorder with a prevalence of about 4% in the Indian population. Hypothyroidismhas been associated with neuropsychiatric symptoms affecting mood & cognitive functions. A relationship has beensuggested between thyroid state and cognition, particularly slowed information processing speed, reduced efficiency inexecutive functions, specific retrieval defects, and poor learning.Aim: To evaluate cognition in newly diagnosed hypothyroid patients & compare with normal euthyroid individuals.Methods: P300 was recorded on 29 newly diagnosed hypothyroid female patients by Galileo NT evoked potentialrecorder using standard odd ball paradigm of acoustic stimuli. Electrodes were put according to the 10-20 InternationalSystem.Cognitive functions were further assessed using colour trails test, triads test & digit vigilance test.Similar procedures were repeated on 29 age & education matched normal euthyroid females.Statistical Analysis was done using SPSS 17 & independent sample “t” test.Results: All the tests showed statistically significant difference (p <0.05) in hypothyroid patients as compared tocontrols.Conclusions: Cognitive decline was observed in hypothyroid patients at diagnosis. This can be detectedelectro-physiologically as well as by institution of appropriate cognitive function tests. Early detection & interventionmay prevent further cognitive decline.
机译：甲状腺功能减退症是一种常见的甲状腺疾病，在印度人口中患病率约为4％。甲状腺功能减退症与影响情绪和认知功能的神经精神症状有关。建议甲状腺状态与认知之间的关系，特别是信息处理速度减慢，执行功能效率降低，特定的检索缺陷和学习不良。目的：评估新诊断的甲状腺功能减退患者的认知并与正常的甲状腺功能正常个体进行比较。由Galileo NT诱发电位记录器对29名新诊断的甲状腺功能减退的女性患者进行了记录，使用的是标准的声刺激奇数球范例。根据10-20国际系统放置电极，通过颜色追踪测试，三合会测试和手指警戒测试进一步评估认知功能，对29名年龄和文化程度相匹配的正常甲状腺功能正常女性重复类似的程序，并使用SPSS 17和结果：所有检查均显示甲状腺功能减退患者与对照组相比有统计学意义（p <0.05）。结论：甲状腺功能减退患者在诊断时认知能力下降。这可以通过电生理学以及通过适当的认知功能测试来检测。早期发现和干预可能会阻止进一步的认知能力下降。

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