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Genetic polymorphisms of 21 STR loci of Goldeneye? DNA ID 22NC kit in five ethnic groups of China

机译:黄金眼21个STR基因座的遗传多态性?中国五个民族的DNA ID 22NC试剂盒

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Short tandem repeats (STRs), polymorphic DNAregions with a variable number of repeated units (2–6base pairs), are attractive to forensic applications suchas human identification and parentage testing [1].Nowadays, most of the commercial STR kits aredesigned based on STRs from the combined DNAindex system (CODIS), European Standard Set (ESS),expanded CODIS, and extended ESS [2]. In this study,we evaluated 21 STRs from Goldeneye TM DNA ID22NC kit (PeopleSpot Inc., Beijing, China), whichincluding 20 polymorphic non-CODIS STR loci (i.e.D1S1656, D2S441, D3S1744, D3S3045, D4S2366,D5S2500, D6S477, D7S1517, D7S3048, D8S1132,D10S1248, D10S1435, D11S2368, D13S325, D14S608,D15S659, D17S1290, D18S535, D19S253, D22GATA198B05)and a CODIS STR locus (D3S1358), in five ethnicgroups (i.e. Eastern Han, Ningxia Hui, Xinjiang Uygur,Xizang Tibetan, and Inner Mongolia Mongolian) ofChina. The forensic genetic investigation of above locimay provide more genetic information in complex kin-ship testing and population studies [3, 4].
机译:短串联重复序列(STR)是具有可变数目的重复单元(2-6个碱基对)的多态性DNA区域,对诸如人类识别和亲子鉴定等法医学应用很有吸引力[1]。如今,大多数商业STR试剂盒都是基于STR设计的来自组合的DNAindex系统(CODIS),欧洲标准集(ESS),扩展的CODIS和扩展的ESS [2]。在这项研究中,我们评估了Goldeneye TM DNA ID22NC试剂盒(中国,北京,PeopleSpot Inc.)中的21个STR,其中包括20个多态性非CODIS STR基因座(即D1S1656,D2S441,D3S1744,D3S3045,D4S2366,D5S2500,D6S477,D7S1517,新疆维吾尔族汉族,新疆维吾尔族,新疆汉族,宁夏,新疆东五里和内蒙古蒙古语)。上述场所的法医遗传学研究为复杂的亲缘关系测试和种群研究提供了更多的遗传信息[3,4]。

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