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首页> 外文期刊>Medicine. >Comparison of clinical outcomes between intravascular optical coherence tomography-guided and angiography-guided stent implantation: A meta-analysis of randomized control trials and systematic review
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Comparison of clinical outcomes between intravascular optical coherence tomography-guided and angiography-guided stent implantation: A meta-analysis of randomized control trials and systematic review

机译：血管内光学相干断层扫描术和血管造影术支架植入术的临床结局比较：随机对照试验和系统评价的荟萃分析

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Objective: This systematic review was designed to evaluate the overall efficacy of optical coherence tomography (OCT)-guided implantation versus angiography -guided for percutaneous coronary intervention . Methods: The following electronic databases, such as CENTRAL, PubMed, Cochrane, and EMBASE were searched for systematic reviews to investigate OCT-guided and angiography -guided implantation. We measured the following 7 parameters in each patient: stent thrombosis, cardiovascular death, myocardial infarction, major adverse cardiac events (MACE), target lesion revascularization (TLR), target vessel revascularization (TVR), all-cause death. Results: In all, 11 studies (6 RCTs and 5 observational studies) involving 4026 subjects were included, with 1903 receiving intravascular ultrasound-guided drug-eluting stent (DES) implantation and 2123 using angiography -guided DES implantation. With regard to MACE, MT, TLR, TVR, stent thrombosis and all-cause death, the group of OCT-guided implantation had no significant statistical association with remarkably improved clinical outcomes. However, its effect on cardiovascular death has a significant statistical difference in angiography -guided implantation group. Conclusion: In the present pool analysis, OCT-guided DES implantation showed a tendency toward improved clinical outcomes compared to angiography -guided implantation. More eligible randomized clinical trials are warranted to verify the findings and to determine the beneficial effect of OCT-guidance for patients.
机译：目的：本系统综述旨在评估光学相干断层扫描（OCT）引导的植入与血管造影引导的经皮冠状动脉介入治疗的总体疗效。方法：搜索以下电子数据库，例如CENTRAL，PubMed，Cochrane和EMBASE，以进行系统评价，以研究OCT引导和血管造影术引导的植入。我们测量了每位患者的以下7个参数：支架血栓形成，心血管死亡，心肌梗塞，主要不良心脏事件（MACE），目标病变血运重建（TLR），目标血管血运重建（TVR），全因死亡。结果：总共包括11项研究（6项RCT和5项观察性研究），涉及4026名受试者，其中1903名接受了血管内超声引导药物洗脱支架（DES）植入，而2123名接受了血管造影术引导的DES植入。关于MACE，MT，TLR，TVR，支架血栓形成和全因死亡，OCT引导的植入组与显着改善的临床结局无显着统计学关联。但是，在血管造影引导的植入组中，其对心血管死亡的影响具有显着的统计学差异。结论：在目前的池分析中，与血管造影术引导的植入相比，OCT引导的DES植入显示出改善临床结果的趋势。有必要进行更多合格的随机临床试验来验证研究结果并确定OCT指南对患者的有益效果。

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