• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>NeuroImage: Clinical >Synchrony of auditory brain responses predicts behavioral ability to keep still in children with autism spectrum disorder
【24h】

Synchrony of auditory brain responses predicts behavioral ability to keep still in children with autism spectrum disorder

机译：听觉脑反应的同步性预测自闭症谱系障碍儿童的行为保持能力

获取原文
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The auditory-evoked P1m, recorded by magnetoencephalography, reflects a central auditory processing ability in human children. One recent study revealed that asynchrony of P1m between the right and left hemispheres reflected a central auditory processing disorder (i.e., attention deficit hyperactivity disorder, ADHD) in children. However, to date, the relationship between auditory P1m right-left hemispheric synchronization and the comorbidity of hyperactivity in children with autism spectrum disorder (ASD) is unknown. In this study, based on a previous report of an asynchrony of P1m in children with ADHD, to clarify whether the P1m right-left hemispheric synchronization is related to the symptom of hyperactivity in children with ASD, we investigated the relationship between voice-evoked P1m right-left hemispheric synchronization and hyperactivity in children with ASD. In addition to synchronization, we investigated the right-left hemispheric lateralization. Our findings failed to demonstrate significant differences in these values between ASD children with and without the symptom of hyperactivity, which was evaluated using the Autism Diagnostic Observational Schedule, Generic (ADOS-G) subscale. However, there was a significant correlation between the degrees of hemispheric synchronization and the ability to keep still during 12-minute MEG recording periods. Our results also suggested that asynchrony in the bilateral brain auditory processing system is associated with ADHD-like symptoms in children with ASD. Highlights ? The auditory-evoked P1m reflects a central auditory processing ability in children. ? This study showed the relationship between P1m and hyperactivity in ASD children. ? There was a correlation between hemispheric synchronization and the ability to keep still during MEG measurement. ? A shorter P1m latency in the right hemisphere was associated with hyperactivity. ? Asynchrony in the brain auditory processing predicts the comorbidity in children with ASD.
机译：通过脑磁图记录的听觉诱发P1m反映了人类儿童的中央听觉处理能力。最近的一项研究表明，左右半球之间的P1m异步反映了儿童的中枢听觉加工障碍（即注意力缺陷多动障碍，ADHD）。然而，迄今为止，自闭症谱系障碍（ASD）儿童的听觉P1m左右半球同步与多动合并症之间的关系尚不清楚。在本研究中，根据先前关于多动症儿童P1m异步的报告，为弄清ASD儿童P1m左右半球同步是否与多动症状有关，我们研究了语音诱发P1m之间的关系。 ASD患儿的左右半球同步性和活动亢进。除了同步之外，我们还研究了左右半球的侧向化。我们的发现未能证明在患有和不患有过度活跃症状的ASD儿童之间，这些值存在显着差异，这是通过使用自闭症诊断性观察性观察表通用（ADOS-G）分量表进行评估的。但是，半球同步度与在12分钟MEG记录期间保持静止的能力之间存在显着的相关性。我们的研究结果还表明，双侧脑听觉处理系统中的异步性与ASD儿童的ADHD样症状有关。强调 ？听觉诱发的P1m反映了儿童的中央听觉处理能力。 ？这项研究显示了ASD儿童中P1m与多动症之间的关系。 ？半球同步与MEG测量期间保持静止的能力之间存在相关性。 ？右半球较短的P1m潜伏期与多动有关。 ？脑听觉处理过程中的异步性可预测ASD儿童的合并症。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号