Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests

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Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests

机译：通过微生物学测试评估了番泻叶（Cassia angustifolia Vahl。）的致突变性和毒性

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Senna (Cassia angustifolia Vahl.) is widely used as laxative, but data from Ames test and animal and/or human studies with this agent have shown a mutagenic and carcinogenic potentiality. Using thee experimental models (bacterial inactivation test; bacterail mutagenisis assay-Mutoxitest; and growth Inhibition test, we investigated the toxicity of senna. Our data suggest an absence of mutagenic and citotoxic potentiality of senna.

机译：番泻叶（Cassia angustifolia Vahl。）被广泛用作泻药，但是来自Ames试验以及使用该药物的动物和/或人体研究的数据显示出诱变和致癌的潜力。使用您的实验模型（细菌灭活试验;细菌诱变试验-Mutoxitest;以及生长抑制试验），我们研究了番泻叶的毒性。我们的数据表明番泻叶没有诱变和细胞毒性潜力。

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《Revista Brasileira de Farmacognosia》 |2004年第14期|共2页
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中图分类临床医学;
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5. Bayesian Methods For Evaluation Of Diagnostic Accuracy Of Quantitative Tests And Disease Diagnosis In The Absence Of A Perfect Reference Standard With Examples From Johne's Disease. [D] . Jafarzadeh, Seyed Reza. 2012

机译：在没有完善的参考标准的情况下，采用贝叶斯方法对定量测试的诊断准确性和疾病诊断进行评估，并附有约翰氏病的实例。
6. Next Generation Sequencing and Transcriptome Analysis Predicts Biosynthetic Pathway of Sennosides from Senna (Cassia angustifolia Vahl.) a Non-Model Plant with Potent Laxative Properties [O] . Nagaraja Reddy Rama Reddy, Rucha Harishbhai Mehta, Palak Harendrabhai Soni, -1

机译：下一代测序和转录组分析预测了番泻叶番泻叶中番石榴苷的生物合成途径番泻叶是具有强泻性特性的非模型植物。
7. Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests [O] . C.R Silva, M.R Monteiro, A. Caldeira-de-Araújo, 2004

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8. Absence of Mutagenicity in the Urine of Autopsy Service Workers Exposed to Formaldehyde: Factors Influencing Mutagenicity Testing of Urine [R] . Connor, T. H. , Ward, J. B. , Legator, M. S. 1985

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Absence of mutagenic and citotoxic potentiality of senna (Cassia angustifolia Vahl.) evaluated by microbiological tests

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