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首页> 外文期刊>Pan African Medical Journal >Neonatal respiratory distress in a reference neonatal unit in Cameroon: an analysis of prevalence, predictors, etiologies and outcomes
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Neonatal respiratory distress in a reference neonatal unit in Cameroon: an analysis of prevalence, predictors, etiologies and outcomes

机译：喀麦隆参考新生儿单位的新生儿呼吸窘迫：患病率，预测因素，病因和结果分析

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Introduction: Neonatal respiratory distress (NRD) is a main cause of neonatal morbidity and mortality in developing countries. Early detection of its risk factors and early treatment of its etiologies are major challenges. However, few studies in developing countries have provided data needed to tackle it. We aimed to determine the prevalence, predictors, etiologies and outcome of NRD in a tertiary health care centre of Cameroon. Methods: We analyzed the hospital files of all newborns admitted to the Neonatal unit of Douala General Hospital from 1st January 2011 to 28th February 2013. NRD was diagnosed based on the presence of one or more of the following signs: an abnormal respiratory rate, expiratory grunting, nasal flaring, chest wall recessions and thoraco-abdominal asynchrony with or without cyanosis, in their files. Socio-demographic and clinical variables of newborns and their mothers were analyzed using logistic regression analysis. Results: The prevalence of NRD was 47.5% out of the 703 newborns studied. Acute fetal distress, elective caesarean delivery, APGAR score < 7 at the 1st minute, prematurity, male gender and macrosomia were independent predictors of NRD. The main etiologies were neonatal infections (31%) and transient tachypnea of the newborn (25%). Its neonatal mortality rate was 24.5%, mainly associated with neonatal sepsis and hyaline membrane disease. Conclusion: NRD is a frequent emergency and causes high morbidity and mortality. Most of its risk factors and etiologies are preventable. Adequate follow-up of pregnancy and labor for timely intervention may improve the neonatal outcomes. Pan African Medical Journal 2016; 24
机译：简介：新生儿呼吸窘迫（NRD）是发展中国家新生儿发病率和死亡率的主要原因。早期发现其危险因素和早期治疗其病因是主要挑战。但是，发展中国家很少有研究提供解决该问题所需的数据。我们旨在确定喀麦隆三级医疗中心的NRD患病率，预测因素，病因和结果。方法：我们分析了2011年1月1日至2013年2月28日在杜阿拉总医院新生儿室收治的所有新生儿的医院档案。根据以下一种或多种体征诊断为NRD：呼吸频率异常，呼气在他们的档案中有咕unt声，鼻翼张开，胸壁凹陷和胸腹异步（有无紫without）。新生儿及其母亲的社会人口统计学和临床​​变量使用逻辑回归分析进行了分析。结果：在研究的703名新生儿中，NRD的患病率为47.5％。急性胎儿窘迫，选择性剖腹产，APGAR在第1分钟得分<7，早产，男性性别和巨大儿是NRD的独立预测因素。主要病因是新生儿感染（31％）和新生儿的短暂呼吸急促（25％）。其新生儿死亡率为24.5％，主要与新生儿败血症和透明膜疾病有关。结论：NRD是一种常见的紧急情况，会导致较高的发病率和死亡率。其大多数危险因素和病因是可以预防的。对妊娠和分娩进行足够的随访以进行及时干预可以改善新生儿结局。泛非医学杂志2016; 24

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