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首页> 外文期刊>The British journal of psychiatry : >Mixed anxiety and depressive disorder outcomes: prospective cohort study in primary care
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Mixed anxiety and depressive disorder outcomes: prospective cohort study in primary care

机译：混合焦虑症和抑郁症结局：基层医疗的前瞻性队列研究

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Background Mixed anxiety and depressive disorder (MADD) is common yet ill-defined, with little known about outcomes. Aims To determine MADD outcomes over 1 year. Method We recruited 250 adults attending seven London general practices with milda€“moderate distress. Three groups were defined using a diagnostic interview: MADD, other ICDa€“10 psychiatric diagnosis, no psychiatric diagnosis. We assessed symptoms of distress (General Health Questionnairea€“28), quality of life (12-item Short Form Health Survey), general practitioner (GP) diagnosis and consultation rate at baseline, 3 months and 1 year. Results Two-thirds of participants with MADD had no significant psychological distress at 3 months (61%) or 1 year (69%). However, compared with those with no diagnosis, individuals had twice the risk of significant distress (incidence rate ratio 2.39, 95% CI 1.29a€“4.42) at 3 months but not 1 year, and persistently lower quality of life (mental health functioning). There was no significant difference in GP consultation rate/diagnosis. Conclusions The majority with MADD improved, but individuals had an increased risk of significant distress at 3 months and a lower quality of life. As we cannot currently predict those with a poorer prognosis these patients should be actively monitored in primary care.
机译：背景焦虑和抑郁综合症（MADD）很常见，但定义不清，对结果知之甚少。目的确定1年以上的MADD结果。方法我们招募了250名成年人，他们参加了7次伦敦轻度中度痛苦的一般做法。使用诊断性访谈定义了三组：MADD，其他ICDa-10精神病诊断，无精神病诊断。我们在基线，3个月和1年时评估了困扰症状（一般健康状况调查表28），生活质量（12项简短健康调查），全科医生（GP）的诊断和咨询率。结果三分之二的MADD参与者在3个月（61％）或1年（69％）时没有明显的心理困扰。但是，与没有诊断的人相比，在3个月而不是1年时，个人遭受重大困扰的风险（发生率比2.39，95％CI 1.29a€4.42）是原来的两倍，并且生活质量不断降低（心理健康功能） ）。 GP咨询率/诊断无明显差异。结论MADD的大多数患者有所改善，但个体在3个月内出现严重困扰的风险增加，生活质量降低。由于我们目前尚无法预测预后较差的患者，因此应在初级保健中积极监测这些患者。

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