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首页> 外文期刊>The Internet Journal of Pharmacology >Perception Of Adverse Drug Reaction Among Doctors, Nurses And Pharmacists Of A Tertiary Care Rural Teaching Hospital
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Perception Of Adverse Drug Reaction Among Doctors, Nurses And Pharmacists Of A Tertiary Care Rural Teaching Hospital

机译：三级农村教学医院的医生，护士和药剂师对药物不良反应的认识

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Introduction: Adverse drug reactions (ADRs) cause wide range of morbidity and mortality. It is estimated that ADRs account for 0.2 – 24% of hospital admissions and 3.7% of patients have fatal ADRs. This objective of the study is to elicit the awareness and reporting of ADRs among health care professionals.Materials and methods: A questionnaire method was adopted to elicit the awareness and reporting of ADRs among Doctors, Nurses and Pharmacists working in a tertiary care rural teaching hospital. After a brief introduction, they were requested to answer each question/ statement. Data were entered in MS excel sheet and analyzed using SPSS package.Results: Of 210 questionnaires distributed, 72 doctors (72%), 34 pharmacists (56.7%), and 23 nurses (46%) returned the questionnaire. Among the respondents, male were more among doctors and pharmacists, and females among nurses. The age and experience of the respondents varied from 30 to 60, and 1 to 30 years respectively. They acquired knowledge on ADRs mainly from books (80%), followed by seminars and symposia (10%). Majority of the respondents agreed that the main cause of ADRs was drugs (70%), and felt allopathy (65%) safer than homeopathy and ayurveda (16%). When asked to rate about their knowledge on ADRs and their reporting, pharmacists rated significantly more than others. About the types of ADRs, 80% of doctors and pharmacists were aware of them, and these were known to 56% of nurses. The respondents felt that antibiotics and NSAIDS were the major cause of ADRs followed by others. The major effects are rashes, abdominal pain, vomiting, etc. These effects are treated by stopping the offending drugs (23%), and administering steroids (10%), antihistamines (18%) and H2 receptor blockers (22%). About 70% of pharmacists have undergone training on reporting of ADRs and seen the reporting form by CDSCO, whereas it was only 13% among doctors and nurses. Only 72% of respondents accepted to report on ADRs on a regular basis.Conclusions: There is a gap between knowledge and reporting of ADRs. Continuous training and motivation are required to increase the reporting of ADRs to Pharmacovigilance centre of the institution. Introduction Every drug has its own beneficial and detrimental effects. While the efficacy of the drug can be quantified with ease, the safety of the drug cannot be quantified2. The dose of the drug determines whether it is a medicine or a poison. Unnecessary and undesirable effects of a drug cause a wide range of morbidity and mortality. Adverse drug reaction has a major impact on public health by imposing a considerable economic burden on the society and the already-stretched health-care systems 13. These effects can be traced back to the Thalidomide disaster14. These effects range from the spontaneous reaction or effects due drug overdose, intolerance, effects due to sudden drug withdrawal, teratological effects, drug abuse etc. It is estimated that ADRs account for 0.2 – 24% of hospital admissions and 3.7% of patients have fatal ADRs15 (Extreme age patients have a higher incidence of ADRs when compared to normal populationRecent estimates suggest ADRs to be the fourth major cause of death in the United States of America (USA). While no official scale exists yet to communicate overall drug risk, the iGuard Drug Risk Rating System (Ref) classifies the drugs into five classes as: Red (high risk), Orange (elevated risk), Yellow (guarded risk) and, Blue (general risk), Green (low risk). The reporting of ADRs could reduce the incidence of ADRs 3.Pharmacovigilance relates to detection, assessment, understanding and prevention of adverse effects or any other drug related problems. The main source of ADR data are spontaneous reporting by doctors, nurses, and Pharmacists from their experiences on ADRs reporting centers prevailing in hospitals, clinical trials including post marketing surveillance and some special studies like case control studies and cohort studies. Spontaneous r
机译：简介：药物不良反应（ADR）导致广泛的发病率和死亡率。据估计，ADR占住院人数的0.2％至24％，而3.7％的患者患有致命的ADR。本研究的目的是引起医疗保健专业人员对ADR的认识和报告。材料和方法：采用问卷调查法在农村三级教学医院工作的医生，护士和药剂师中引起ADR的认识和报告。 。简要介绍之后，请他们回答每个问题/陈述。结果：在分发的210张问卷中，有72位医生（72％），34位药剂师（56.7％）和23位护士（46％）返回了问卷。在受访者中，医生和药剂师中男性更多，而护士中女性更多。受访者的年龄和经验分别为30至60岁和1至30岁。他们主要从书籍中获取有关ADR的知识（80％），其次是研讨会和专题讨论会（10％）。大多数受访者同意，ADR的主要原因是药物（70％），并且感觉同种疗法（65％）比顺势疗法和阿育吠陀（16％）更安全。当被要求对他们在ADR和报告方面的知识进行评分时，药剂师的评分要比其他人高得多。关于ADR的类型，80％的医生和药剂师都知道它们，而56％的护士都知道。受访者认为抗生素和非甾体抗炎药是引起ADR的主要原因，其次是其他药物。主要作用是皮疹，腹痛，呕吐等。这些作用可通过停止使用有问题的药物（23％），并使用类固醇（10％），抗组胺药（18％）和H2受体阻滞剂（22％）来治疗。大约70％的药剂师已经接受过有关ADR报告的培训，并看过CDSCO的报告表格，而在医生和护士中只有13％。结论：只有72％的受访者接受定期报告ADR。结论：ADR的知识与报告之间存在差距。需要不断的培训和激励，以增加向该机构的药物警戒中心报告ADR的情况。简介每种药物都有其自身的有益和有害作用。虽然可以轻松量化药物的功效，但不能量化药物的安全性2。药物的剂量决定了它是药物还是毒药。药物的不必要和不良影响会导致广泛的发病率和死亡率。药物不良反应通过给社会和已经紧张的医疗体系造成相当大的经济负担，对公共卫生产生了重大影响。这些影响可以追溯到萨利多米德灾难14。这些影响包括自发反应或药物过量引起的影响，不耐受，突然停药引起的影响，致畸作用，药物滥用等。据估计，ADR占住院人数的0.2％至24％，而致命的患者占3.7％ ADRs15（与正常人群相比，极端年龄患者的ADR发生率更高。最新估计表明，ADR是美国（美国）的第四大主要死因。虽然尚无官方的量表来传达总体药物风险，但iGuard药物风险评估系统（Ref）将药物分为五类：红色（高风险），橙色（高风险），黄色（有保障的风险）和蓝色（一般风险），绿色（低风险）。 ADR可以减少ADR的发生3.药物警戒与不良反应或任何其他药物相关问题的检测，评估，理解和预防有关，ADR数据的主要来源是医生自发报告。 ses和药剂师在医院中普遍使用的ADR报告中心的经验，临床试验（包括上市后监测）以及一些特殊研究（如病例对照研究和队列研究）的过程中。自发的

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