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首页> 外文期刊>The Internet Journal of Academic Physician Assistants >A study of women and mothers’- of- minor- age- daughters knowledge of HPV as well as the attitudes toward the HPV vaccine
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A study of women and mothers’- of- minor- age- daughters knowledge of HPV as well as the attitudes toward the HPV vaccine

机译：对妇女和母亲的HPV知识以及对HPV疫苗的态度进行的研究

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Background— The Human papillomavirus (HPV) is a common sexually transmitted infection that generally goes unnoticed due to a lack of symptoms; however, HPV can lead to anogenital warts and, in chronic cases, cervical cancer. The Merck pharmaceutical company developed a commercial version of a quadrivalent recombinant non-infectious vaccine that was tested in preclinical research. This vaccine targets serotypes HPV16 and HPV18, which cause an estimated 70% of all cervical cancers, as well as serotypes HPV6 and HPV11, which cause 90% of external genital warts.3 In June 2006 the FDA approved Gardasila, an HPV immunization for use in females aged 9 to 26 years. Aim—This project aims to examine the current understanding and beliefs of the women surveyed and provide a base which healthcare professionals can use to aid in expanding women’s general knowledge about this virus and its prevention.Methods— A cross-sectional survey was conducted among women across Texas aged 17 years and above. Approximately 200 women from two different groups were approached at random and asked to participate in a survey examining their knowledge, attitudes, and beliefs about HPV and the new HPV vaccine known as Gardasil?. These were termed Group 1 (women ages 17-26 years) and Group 2 (mothers of girls ages 9-16). After collection, the data was interpreted using the Statistical Package for the Social Sciences (SPSS) and the results were presented as frequencies (%) or means and standard deviations, as appropriate.Results—The majority of both groups knew that HPV was a sexually transmitted infection that could cause cervical cancer, but far fewer recognized other long-term effects. Television was the most commonly cited information source in both groups, and most knew that Gardasil? was a preventive step, not a treatment. Concern over side effects and cost were the most influential factors in choosing whether to get Gardasil?, not religious beliefs or value systems. Most women thought the vaccine worth the high price but worried about whether they could afford it even so.Conclusion—While awareness and knowledge is increasing, much education is still needed about risk factor awareness and potential vaccine side effects. By making Gardasil? more affordable to the public the use of the vaccine would likely increase. Statewide acceptance is likely to be fostered by the absence of major side effects and the release of a generic form. Introduction The Human papillomavirus (HPV) is a DNA virus that is known to be the most common sexually transmitted infection in the United States. It is estimated that this virus affects about 75% of sexually active adults in America.1 Generally, most HPV infections go unnoticed due to a lack of HPV related symptoms; however, HPV can lead to anogenital warts and in chronic cases it can lead to cervical cancer. Although the HPV virus has over 100 different serotypes, not all are known to cause cancer. In particular, a group of approximately 30 different serotypes are passed through sexual contact. Of those 30, serotypes 6 and 11 have been recognized as causing genital warts. Furthermore, 13 of the serotypes are known as “high risk” due to their ability to cause cervical dysplasia, which in time can lead to cancer.2 These 13 types differ from the ones that are known to cause the genital warts alone. A recent report stated that 93% of invasive cervical cancers worldwide contain Human papillomavirus (HPV). 2 According to a 2002 study that evaluated various infection induced cancers, cervical cancers had approximately 500,000 incidences. HPV was the causative factor in each of those 500,000 incidences. In response to this potentially life threatening virus and its persistence, Merck developed a commercial version of a quadrivalent recombinant non-infectious vaccine that was tested in preclinical research. This vaccine targets serotypes HPV16 and HPV18, which have been confirmed to cause an estimated 70% of all cervical cancers. This qu
机译：背景技术人乳头瘤病毒（HPV）是一种常见的性传播感染，由于缺乏症状而通常不会引起注意。但是，HPV会导致肛门生殖器疣，在慢性病例中会导致宫颈癌。默克制药公司开发了商业版的四价重组非感染性疫苗，该疫苗已在临床前研究中进行了测试。该疫苗的靶标是血清型HPV16和HPV18，它们导致大约70％的宫颈癌，以及血清型HPV6和HPV11，其引起90％的外部生殖器疣。32006年6月，FDA批准了使用HPV的Gardasila疫苗。 9至26岁的女性。目的—该项目旨在检查被调查妇女的当前理解和信念，并为医疗保健专业人员提供基础，以帮助扩大妇女对该病毒及其预防的一般知识。方法—对妇女进行了横断面调查在德克萨斯州，年龄在17岁以上。随机抽取了来自两个不同群体的大约200名妇女，要求他们参加一项调查，以调查她们对HPV和新的HPV疫苗Gardasil？的知识，态度和信念。这些被称为第一组（17-26岁的妇女）和第二组（9-16岁的女孩的母亲）。收集后，使用社会科学统计软件包（SPSS）解释数据，并酌情以频率（％）或均值和标准差的形式表示结果。结果-两组中的大多数都知道HPV是性可以导致子宫颈癌的传染病传播，但其他长期影响却很少。电视是两组中最常被引用的信息来源，并且大多数人都知道Gardasil？是预防步骤，不是治疗方法。在选择是否获得Gardasil时，对副作用和成本的关注是最有影响力的因素，而不是宗教信仰或价值体系。大多数妇女认为疫苗值得高价，但担心自己是否能负担得起。结论—尽管人们的认识和知识在不断增加，但仍需要对危险因素的认识和潜在的疫苗副作用进行大量教育。通过制作Gardasil？对于公众而言更负担得起的疫苗的使用可能会增加。没有主要的副作用和发布通用形式，可能会促进全州范围的接受。简介人乳头瘤病毒（HPV）是一种DNA病毒，已知是美国最常见的性传播感染。据估计，这种病毒影响了美国约75％的性活跃成年人。1通常，由于缺乏与HPV相关的症状，大多数HPV感染不会被注意到。但是，HPV会导致肛门生殖器疣，在慢性病例中会导致宫颈癌。尽管HPV病毒具有100多种不同的血清型，但并非所有人都可致癌。特别是，一组大约30种不同的血清型通过性接触传播。在这30种中，血清型6和11被认为是引起尖锐湿疣的原因。此外，有13种血清型由于其引起宫颈发育异常的能力而被称为“高危”，这会导致癌症。2这13种血清型不同于已知的仅导致尖锐湿疣的类型。最近的一份报告指出，全世界93％的浸润性宫颈癌包含人类乳头瘤病毒（HPV）。 2根据2002年的一项评估各种感染引起的癌症的研究，子宫颈癌的发病率约为500,000。在这500,000次发病中，HPV是致病因素。针对这种潜在的威胁生命的病毒及其持久性，默克公司开发了商业版的四价重组非感染性疫苗，并在临床前研究中对其进行了测试。该疫苗针对的是HPV16和HPV18血清型，这些血清型已被证实可引起所有子宫颈癌的70％。这个曲

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