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首页> 外文期刊>Hong Kong Journal of Paediatrics >Probiotics Provoked D-lactic Acidosis in Short Bowel Syndrome: Case Report and Literature Review
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Probiotics Provoked D-lactic Acidosis in Short Bowel Syndrome: Case Report and Literature Review

机译：益生菌在短肠综合征中引发D-乳酸性酸中毒：病例报告和文献综述

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摘要

D-lactic acidosis is a rare complication of short bowel syndrome. Clinically there are episodes of encephalopathy and metabolic acidosis with an increased anion gap. Formation of D-lactic acid by the abnormal gut flora, together with its impaired metabolism results in its accumulation and subsequent effect on the central nervous system. In this article we reported a boy with short bowel syndrome and D-lactic acidosis provoked by ingestion of probiotics. The probiotics are in the form of capsules and probiotic-containing formula. We had also reviewed the paediatric cases of D-lactic acidosis and discussed its biochemistry, pathogenesis, clinical features, diagnosis and treatment. With more understanding of its mechanism, we stated that D-lactic acidosis can be treated as well as provoked by probiotics.
机译：D-乳酸性酸中毒是短肠综合征的罕见并发症。临床上会出现脑病和代谢性酸中毒，阴离子间隙增加。异常肠道菌群形成D-乳酸及其代谢受损会导致D-乳酸的积累并随后对中枢神经系统产生影响。在本文中，我们报道了一个男孩因摄入益生菌而引起的短肠综合症和D-乳酸性酸中毒。益生菌为胶囊和含益生菌配方的形式。我们还回顾了D-乳酸性酸中毒的儿科病例，并讨论了其生物化学，发病机理，临床特征，诊断和治疗。进一步了解其机制后，我们说D-乳酸性酸中毒既可以被益生菌治疗也可以被激发。

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