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首页> 外文期刊>The Egyptian Journal of Neurology, Psychiatry and Neurosurgery >Effect of Age, Sex, Body Mass Index and Smoking on Carotid Intima Media Thickness in Normal Egyptians
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Effect of Age, Sex, Body Mass Index and Smoking on Carotid Intima Media Thickness in Normal Egyptians

机译：年龄，性别，体重指数和吸烟对正常埃及人颈动脉内膜中层厚度的影响

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Background: Carotid artery intima media thickness (CIMT) represents a marker for sub-clinical atherosclerosis. Objective: To explore the possible effects of age, sex, body mass index (BMI) and smoking on IMT of the carotid artery in normal Egyptian subjects. Methods: A total of 101 normal healthy Egyptian subjects underwent duplex ultrasonography of the carotid artery for assessment of intima media thickness. All subjects underwent measurement of BMI, smoking status, serum cholesterol, triglycerides. Results: A statistically high significant difference was observed between age groups as regards right, left and average CIMT. A highly significant positive correlation was detected between mean age and Right, Left, and average CIMT. A statistically highly significant difference was observed between female and male participants as regards mean Right, Left, and average carotid IMT, being significantly thinner in females. A statistically significant difference was found between non-smoker group and both ex-smoker and smoker groups as regards the mean Left CIMT. A statistically high significant positive correlation was found between duration of smoking and Right, Left and average CIMT. No significant differences were detected between subjects of different BMI groups as regards CIMT. Age and interaction of age with smoking were found to be the only independent factors affecting the CIMT in both males and females. Conclusion: In normal Egyptian subjects, age is a significant predictor for increased CIMT in both males and females. Smoking duration is a significant predictor for increased CIMT in males. Age, smoking and interaction of age with smoking were found to be the only independent factors for increased CIMT. [Egypt J Neurol Psychiat Neurosurg.  2011; 48(2): 191-198]
机译：背景：颈动脉内膜中层厚度（CIMT）代表亚临床动脉粥样硬化的标志物。目的：探讨年龄，性别，体重指数（BMI）和吸烟对正常埃及受试者颈动脉IMT的可能影响。方法：总共101名健康的埃及健康受试者接受了颈动脉的双重超声检查以评估内膜中层厚度。所有受试者均接受BMI，吸烟状况，血清胆固醇，甘油三酸酯的测量。结果：各年龄组在左右CIMT和平均CIMT之间观察到统计学上的显着差异。在平均年龄与右，左和平均CIMT之间发现高度显着的正相关。在女性参与者和男性参与者之间，就平均右，左和平均颈动脉IMT而言，观察到统计学上高度显着的差异，女性明显更薄。在非吸烟者组与既往吸烟者和吸烟者组之间，就平均左CIMT而言，存在统计学上的显着差异。吸烟时间与右，左和平均CIMT之间存在统计学上的显着正相关。在CIMT方面，在不同BMI组的受试者之间未检测到显着差异。年龄和年龄与吸烟的相互作用被发现是影响男性和女性CIMT的唯一独立因素。结论：在正常的埃及受试者中，年龄是男性和女性CIMT升高的重要预测因子。吸烟时间是男性CIMT升高的重要预测指标。发现年龄，吸烟和年龄与吸烟的相互作用是CIMT升高的唯一独立因素。 [埃及J Neurol精神病神经外科。 2011; 48（2）：191-198]

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