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首页> 外文期刊>Journal of International Medical Research >Intrathecal bupivacaine or levobupivacaine: Which should be used for elderly patients?
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Intrathecal bupivacaine or levobupivacaine: Which should be used for elderly patients?

机译：鞘内注射布比卡因或左布比卡因：老年患者应使用哪种？

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Objectives To compare two intrathecal anaesthetics, bupivacaine and levobupivacaine, for their effects on motor and sensory blockade and haemodynamics in patients aged ≥65 years undergoing transurethral resection of the prostate (TUR-P) or transurethral resection of the urinary bladder (TUR-M). Methods Patients scheduled to undergo TUR-P or TUR-M were randomized to receive either 3?ml (15?mg) 0.5% isobaric levobupivacaine (group L) or 3?ml (15?mg) of 0.5% hyperbaric bupivacaine (group B) for spinal anaesthesia. The onset time, maximum level and time to reach the maximum level of sensory and motor blockade were recorded. Changes to haemodynamic parameters were also recorded. Results The study randomized 100 patients: 57 to group L and 43 to group B. Levobupivacaine did not cause any significant changes in haemodynamic parameters, including systolic blood pressure, and showed a similar sensory block onset time compared with bupivacaine, but it had a significantly longer motor block onset time compared with bupivacaine. Conclusion These current findings suggest that levobupivacaine can be used as a substitute for bupivacaine for spinal anaesthesia in elderly patients ≥65 years of age undergoing elective TUR-P or TUR-M operations.
机译：目的比较两种鞘内麻醉药布比卡因和左旋布比卡因对≥65岁接受前列腺电切术（TUR-P）或经尿道膀胱电切术（TUR-M）的患者的运动和感觉阻滞及血流动力学的影响。方法计划接受TUR-P或TUR-M治疗的患者被随机分配接受3？ml（15？mg）0.5％的等压左旋布比卡因（L组）或3？ml（15？mg）的0.5％高压布比卡因（B组）。 ）进行脊髓麻醉。记录起效时间，最大水平和达到最大感觉和运动阻滞水平的时间。还记录了血流动力学参数的变化。结果该研究将100例患者随机分组：L组57例，B组43例。左旋布比卡因没有引起血液动力学参数（包括收缩压）的任何显着变化，并且与布比卡因相比具有相似的感觉阻滞发作时间，但具有显着的意义。与布比卡因相比，运动阻滞发作时间更长。结论这些最新发现表明，左旋布比卡因可替代布比卡因用于接受选择性TUR-P或TUR-M手术的65岁以上老年患者的脊柱麻醉。

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